GO Annotations Graph

• Symbol: Il2rb
• Name: interleukin 2 receptor, beta chain
• ID: MGI:96550

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015026	coreceptor activity	ISO	J:164563
Molecular Function	GO:0004896	cytokine receptor activity	IBA	J:265628
Molecular Function	GO:0042010	interleukin-15 receptor activity	ISO	J:164563
Molecular Function	GO:0019976	interleukin-2 binding	ISO	J:164563
Molecular Function	GO:0019976	interleukin-2 binding	ISO	J:155856
Molecular Function	GO:0019976	interleukin-2 binding	IPI	J:16175
Molecular Function	GO:0004911	interleukin-2 receptor activity	ISO	J:155856
Molecular Function	GO:0004911	interleukin-2 receptor activity	ISO	J:73065
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:164687
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:152384
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:91304
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:16175
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:112035
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:190936
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:140498
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:112602
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8983294
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8983313
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8983356
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9007126
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9007137
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9009867
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:73065
Biological Process	GO:0016064	immunoglobulin mediated immune response	IBA	J:265628
Biological Process	GO:0035723	interleukin-15-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0038110	interleukin-2-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0030101	natural killer cell activation	ISO	J:155856
Biological Process	GO:0030101	natural killer cell activation	IBA	J:265628
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:73065
Biological Process	GO:0050766	positive regulation of phagocytosis	ISO	J:164563