GO Annotations Graph

• Symbol: Il7r
• Name: interleukin 7 receptor
• ID: MGI:96562

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004896	cytokine receptor activity	ISO	J:164563
Molecular Function	GO:0004896	cytokine receptor activity	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:99189
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:155686
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:144049
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:84890
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92679
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-1295758
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-1295764
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-1295768
Biological Process	GO:0001782	B cell homeostasis	IGI	J:99189
Biological Process	GO:0001782	B cell homeostasis	IGI	J:99189
Biological Process	GO:0042100	B cell proliferation	IGI	J:99189
Biological Process	GO:0042100	B cell proliferation	IMP	J:99189
Biological Process	GO:0042100	B cell proliferation	IGI	J:99189
Biological Process	GO:0000902	cell morphogenesis	IGI	J:99189
Biological Process	GO:0000902	cell morphogenesis	IGI	J:99189
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:161481
Biological Process	GO:0010467	gene expression	IMP	J:144049
Biological Process	GO:0030097	hemopoiesis	IBA	J:265628
Biological Process	GO:0002377	immunoglobulin production	IGI	J:99189
Biological Process	GO:0002377	immunoglobulin production	IGI	J:99189
Biological Process	GO:0048535	lymph node development	IMP	J:83288
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	IMP	J:41239
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity	IMP	J:41239
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:144049
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	IBA	J:265628
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT	ISO	J:164563
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	IMP	J:41241
Biological Process	GO:0008361	regulation of cell size	IGI	J:99189
Biological Process	GO:0008361	regulation of cell size	IGI	J:99189
Biological Process	GO:0008361	regulation of cell size	IDA	J:99189
Biological Process	GO:0008361	regulation of cell size	IGI	J:99189
Biological Process	GO:0008361	regulation of cell size	IGI	J:99189
Biological Process	GO:0030217	T cell differentiation	IMP	J:41239
Biological Process	GO:0030217	T cell differentiation	IGI	J:41239
Biological Process	GO:0030217	T cell differentiation	IMP	J:41239
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:41241
Biological Process	GO:0043029	T cell homeostasis	IMP	J:41239
Biological Process	GO:0043029	T cell homeostasis	IMP	J:41239
Biological Process	GO:0043029	T cell homeostasis	IMP	J:41241
Biological Process	GO:0001913	T cell mediated cytotoxicity	IMP	J:41239
Biological Process	GO:0001913	T cell mediated cytotoxicity	IMP	J:41239
Biological Process	GO:0001913	T cell mediated cytotoxicity	IMP	J:41239