GO Annotations Graph

• Symbol: Inhbb
• Name: inhibin beta-B
• ID: MGI:96571

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	IEA	J:72247
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0005179	hormone activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0071944	cell periphery	IDA	J:17302
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2470487
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2470495
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:17302
Biological Process	GO:0032924	activin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0030509	BMP signaling pathway	IBA	J:265628
Biological Process	GO:0071397	cellular response to cholesterol	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	IEP	J:163437
Biological Process	GO:0044320	cellular response to leptin stimulus	IEP	J:163437
Biological Process	GO:0009267	cellular response to starvation	IEP	J:163437
Biological Process	GO:0001654	eye development	TAS	J:63882
Biological Process	GO:0045444	fat cell differentiation	IEP	J:163437
Biological Process	GO:0046882	negative regulation of follicle-stimulating hormone secretion	ISO	J:164563
Biological Process	GO:0032686	negative regulation of hepatocyte growth factor production	ISO	J:164563
Biological Process	GO:0046676	negative regulation of insulin secretion	IMP	J:136342
Biological Process	GO:0048599	oocyte development	IGI	J:160549
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0046881	positive regulation of follicle-stimulating hormone secretion	ISO	J:164563
Biological Process	GO:0060279	positive regulation of ovulation	IMP	J:125354
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA	J:265628
Biological Process	GO:0060395	SMAD protein signal transduction	IBA	J:265628