GO Annotations Graph

• Symbol: Itga3
• Name: integrin alpha 3
• ID: MGI:96602

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005518	collagen binding	ISO	J:155856
Molecular Function	GO:0001968	fibronectin binding	ISO	J:155856
Molecular Function	GO:0005178	integrin binding	ISO	J:155856
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0043236	laminin binding	ISO	J:155856
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:273548
Molecular Function	GO:0005515	protein binding	IPI	J:126749
Molecular Function	GO:0005515	protein binding	IPI	J:84858
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:23945
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:75058
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0060076	excitatory synapse	IDA	J:196653
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:47279
Cellular Component	GO:0031527	filopodium membrane	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:254944
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:254944
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:1990812	growth cone filopodium	ISO	J:155856
Cellular Component	GO:0034667	integrin alpha3-beta1 complex	ISO	J:164563
Cellular Component	GO:0034667	integrin alpha3-beta1 complex	ISO	J:155856
Cellular Component	GO:0008305	integrin complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031594	neuromuscular junction	IMP	J:251846
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:251846
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:251846
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:251846
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:251846
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:86627
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:251846
Cellular Component	GO:0048787	presynaptic active zone membrane	IDA	J:251846
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0045202	synapse	IDA	J:84858
Cellular Component	GO:0097060	synaptic membrane	IDA	J:196653
Biological Process	GO:0007610	behavior	IMP	J:196653
Biological Process	GO:0007155	cell adhesion	ISO	J:155856
Biological Process	GO:0033627	cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0097062	dendritic spine maintenance	IGI	J:196653
Biological Process	GO:0097062	dendritic spine maintenance	IMP	J:196653
Biological Process	GO:0035640	exploration behavior	IGI	J:196653
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0050900	leukocyte migration	IBA	J:265628
Biological Process	GO:0030324	lung development	ISO	J:164563
Biological Process	GO:0007613	memory	IMP	J:84858
Biological Process	GO:0031345	negative regulation of cell projection organization	ISO	J:155856
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0072006	nephron development	ISO	J:164563
Biological Process	GO:0001764	neuron migration	IMP	J:90026
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0010634	positive regulation of epithelial cell migration	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0099173	postsynapse organization	IDA	J:254944
Biological Process	GO:0099173	postsynapse organization	IMP	J:254944
Biological Process	GO:0030510	regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030111	regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0097205	renal filtration	ISO	J:164563
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0043588	skin development	ISO	J:164563
Biological Process	GO:0099560	synaptic membrane adhesion	IMP	J:251846
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:251846
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:251846