Itga4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Itga4
integrin alpha 4
MGI:96603

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003823	antigen binding	ISO	J:155856
Molecular Function	GO:0019960	C-X3-C chemokine binding	ISO	J:164563
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:155856
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0001968	fibronectin binding	ISO	J:155856
Molecular Function	GO:0001968	fibronectin binding	IMP	J:125142
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:1990405	protein antigen binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	TAS	J:169941
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:197681
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:125138
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:23140
Cellular Component	GO:0070062	extracellular exosome	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0034669	integrin alpha4-beta7 complex	ISO	J:164563
Cellular Component	GO:0008305	integrin complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0060385	axonogenesis involved in innervation	ISO	J:155856
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:108464
Biological Process	GO:0007155	cell adhesion	IMP	J:76747
Biological Process	GO:0033627	cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0016477	cell migration	IMP	J:76747
Biological Process	GO:0098609	cell-cell adhesion	TAS	J:169941
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0140039	cell-cell adhesion in response to extracellular stimulus	ISO	J:164563
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	TAS	J:169941
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration	ISO	J:164563
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:164563
Biological Process	GO:0060710	chorio-allantoic fusion	IMP	J:23140
Biological Process	GO:1990771	clathrin-dependent extracellular exosome endocytosis	ISO	J:155856
Biological Process	GO:0050904	diapedesis	ISO	J:155856
Biological Process	GO:0060324	face development	IMP	J:23140
Biological Process	GO:0007507	heart development	IMP	J:23140
Biological Process	GO:0007507	heart development	IMP	J:76747
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	J:125142
Biological Process	GO:0034113	heterotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:0098657	import into cell	ISO	J:155856
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0007159	leukocyte cell-cell adhesion	ISO	J:164563
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IMP	J:125139
Biological Process	GO:0050901	leukocyte tethering or rolling	ISO	J:164563
Biological Process	GO:0060485	mesenchyme development	TAS	J:169941
Biological Process	GO:0090074	negative regulation of protein homodimerization activity	ISO	J:164563
Biological Process	GO:1990138	neuron projection extension	ISO	J:155856
Biological Process	GO:1905351	pericyte cell migration	IMP	J:108464
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:1903039	positive regulation of leukocyte cell-cell adhesion	ISO	J:155856
Biological Process	GO:0002687	positive regulation of leukocyte migration	ISO	J:155856
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	ISO	J:155856
Biological Process	GO:2000406	positive regulation of T cell migration	ISO	J:155856
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0043113	receptor clustering	ISO	J:164563
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0072678	T cell migration	IMP	J:199126
Biological Process	GO:0072678	T cell migration	IMP	J:199126
Biological Process	GO:1904738	vascular associated smooth muscle cell migration	IMP	J:108464
Biological Process	GO:0061032	visceral serous pericardium development	TAS	J:169941

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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