GO Annotations Graph

• Symbol: Itga6
• Name: integrin alpha 6
• ID: MGI:96605

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031994	insulin-like growth factor I binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0043236	laminin binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0038132	neuregulin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:273507
Molecular Function	GO:0005515	protein binding	IPI	J:59402
Molecular Function	GO:0005515	protein binding	IPI	J:233591
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Molecular Function	GO:0005515	protein binding	IPI	J:126749
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	ISO	J:155856
Cellular Component	GO:0045178	basal part of cell	IDA	J:74274
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:71478
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:171374
Cellular Component	GO:0005604	basement membrane	IDA	J:46802
Cellular Component	GO:0005604	basement membrane	IDA	J:46802
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:75058
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:16243
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:148710
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:158532
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:47279
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:125138
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0030056	hemidesmosome	IDA	J:181275
Cellular Component	GO:0034676	integrin alpha6-beta4 complex	ISO	J:155856
Cellular Component	GO:0008305	integrin complex	IBA	J:265628
Cellular Component	GO:0008305	integrin complex	IDA	J:77644
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:215661
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:75058
Cellular Component	GO:0005886	plasma membrane	IDA	J:82124
Cellular Component	GO:0005886	plasma membrane	IDA	J:15225
Cellular Component	GO:0005886	plasma membrane	IDA	J:82761
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:137608
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0033627	cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:155856
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:108325
Biological Process	GO:0031589	cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0031668	cellular response to extracellular stimulus	IDA	J:54434
Biological Process	GO:0046847	filopodium assembly	IMP	J:108325
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0050900	leukocyte migration	IBA	J:265628
Biological Process	GO:0050900	leukocyte migration	IGI	J:26920
Biological Process	GO:0050900	leukocyte migration	IGI	J:26920
Biological Process	GO:0050900	leukocyte migration	IMP	J:26839
Biological Process	GO:0097534	lymphoid lineage cell migration	IMP	J:26839
Biological Process	GO:0035878	nail development	ISO	J:164563
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:108325
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:73065
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IDA	J:125140
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	IMP	J:273507
Biological Process	GO:0042327	positive regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0043589	skin morphogenesis	ISO	J:164563