GO Annotations Graph

• Symbol: Itgb5
• Name: integrin beta 5
• ID: MGI:96614

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005178	integrin binding	IPI	J:175331
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0005178	integrin binding	IPI	J:31981
Molecular Function	GO:0005515	protein binding	IPI	J:213636
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Cellular Component	GO:0031252	cell leading edge	IDA	J:142596
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	IDA	J:142596
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105648
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105648
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105648
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:105648
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105648
Cellular Component	GO:0034684	integrin alphav-beta5 complex	IDA	J:175331
Cellular Component	GO:0034684	integrin alphav-beta5 complex	ISO	J:164563
Cellular Component	GO:0008305	integrin complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-2731130
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0097060	synaptic membrane	IDA	J:105648
Cellular Component	GO:0097060	synaptic membrane	IDA	J:105648
Cellular Component	GO:0097060	synaptic membrane	IDA	J:105648
Cellular Component	GO:0097060	synaptic membrane	IDA	J:105648
Cellular Component	GO:0097060	synaptic membrane	IEP	J:105648
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0033627	cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0090136	epithelial cell-cell adhesion	ISO	J:164563
Biological Process	GO:0007229	integrin-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0007229	integrin-mediated signaling pathway	IMP	J:213085
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0043149	stress fiber assembly	ISO	J:164563
Biological Process	GO:0043149	stress fiber assembly	IMP	J:213085
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IMP	J:213085