GO Annotations Graph

• Symbol: Itgb6
• Name: integrin beta 6
• ID: MGI:96615

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0005178	integrin binding	IPI	J:31981
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:110369
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:47279
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0034685	integrin alphav-beta6 complex	IDA	J:210448
Cellular Component	GO:0034685	integrin alphav-beta6 complex	ISO	J:164563
Cellular Component	GO:0034685	integrin alphav-beta6 complex	IBA	J:265628
Cellular Component	GO:0008305	integrin complex	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0060348	bone development	IMP	J:295593
Biological Process	GO:0060435	bronchiole development	IDA	J:89578
Biological Process	GO:0060435	bronchiole development	IMP	J:89578
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0033627	cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0033627	cell adhesion mediated by integrin	IDA	J:210448
Biological Process	GO:0033627	cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0000902	cell morphogenesis	IMP	J:141644
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:200222
Biological Process	GO:0071479	cellular response to ionizing radiation	IDA	J:147819
Biological Process	GO:0002534	cytokine production involved in inflammatory response	IMP	J:295593
Biological Process	GO:0070166	enamel mineralization	IMP	J:200222
Biological Process	GO:0010467	gene expression	IMP	J:89578
Biological Process	GO:0010467	gene expression	IMP	J:200222
Biological Process	GO:0010467	gene expression	IMP	J:295593
Biological Process	GO:0060022	hard palate development	IGI	J:145991
Biological Process	GO:0006955	immune response	IGI	J:145991
Biological Process	GO:0006954	inflammatory response	IMP	J:100142
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0061520	Langerhans cell differentiation	IGI	J:145991
Biological Process	GO:0048286	lung alveolus development	IDA	J:89578
Biological Process	GO:0048286	lung alveolus development	IMP	J:89578
Biological Process	GO:0055091	phospholipid homeostasis	IMP	J:141644
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	ISO	J:164563
Biological Process	GO:0009615	response to virus	IGI	J:281014
Biological Process	GO:0009611	response to wounding	IDA	J:297353
Biological Process	GO:0009611	response to wounding	IDA	J:310321
Biological Process	GO:0043588	skin development	IMP	J:89578
Biological Process	GO:0060395	SMAD protein signal transduction	IDA	J:295593
Biological Process	GO:0043129	surfactant homeostasis	IMP	J:141644
Biological Process	GO:0071604	transforming growth factor beta production	IDA	J:210448
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IMP	J:89578
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:281014
Biological Process	GO:0042060	wound healing	IMP	J:297361
Biological Process	GO:0042060	wound healing	IMP	J:297361