GO Annotations Graph

• Symbol: Jup
• Name: junction plakoglobin
• ID: MGI:96650

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045294	alpha-catenin binding	ISO	J:164563
Molecular Function	GO:0045294	alpha-catenin binding	IBA	J:265628
Molecular Function	GO:0045294	alpha-catenin binding	IPI	J:87110
Molecular Function	GO:0045296	cadherin binding	ISO	J:164563
Molecular Function	GO:0045296	cadherin binding	IBA	J:265628
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0106006	cytoskeletal protein-membrane anchor activity	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:87593
Molecular Function	GO:0005515	protein binding	IPI	J:114547
Molecular Function	GO:0005515	protein binding	IPI	J:87110
Molecular Function	GO:0005515	protein binding	IPI	J:85670
Molecular Function	GO:0005515	protein binding	IPI	J:85670
Molecular Function	GO:0005515	protein binding	IPI	J:85670
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0019903	protein phosphatase binding	IBA	J:265628
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005198	structural molecule activity	IEA	J:72247
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:29881
Cellular Component	GO:0005912	adherens junction	IDA	J:97223
Cellular Component	GO:0016327	apicolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016342	catenin complex	ISO	J:164563
Cellular Component	GO:0016342	catenin complex	IBA	J:265628
Cellular Component	GO:0016342	catenin complex	IDA	J:35077
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	IDA	J:85670
Cellular Component	GO:0005911	cell-cell junction	IDA	J:143362
Cellular Component	GO:0005911	cell-cell junction	IDA	J:170926
Cellular Component	GO:0001533	cornified envelope	IDA	J:230728
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:85670
Cellular Component	GO:0030057	desmosome	ISO	J:164563
Cellular Component	GO:0030057	desmosome	ISO	J:155856
Cellular Component	GO:0030057	desmosome	IMP	J:177567
Cellular Component	GO:0030057	desmosome	IDA	J:60391
Cellular Component	GO:0030057	desmosome	IMP	J:148138
Cellular Component	GO:0030057	desmosome	IDA	J:60391
Cellular Component	GO:0030057	desmosome	IDA	J:97223
Cellular Component	GO:0030057	desmosome	IDA	J:87593
Cellular Component	GO:0030057	desmosome	IDA	J:51903
Cellular Component	GO:0005916	fascia adherens	ISO	J:155856
Cellular Component	GO:0071665	gamma-catenin-TCF7L2 complex	ISO	J:164563
Cellular Component	GO:0014704	intercalated disc	ISO	J:164563
Cellular Component	GO:0005882	intermediate filament	IDA	J:125067
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Cellular Component	GO:0030018	Z disc	IDA	J:33980
Cellular Component	GO:0030018	Z disc	IDA	J:33980
Biological Process	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IDA	J:85670
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:164563
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:38047
Biological Process	GO:0071681	cellular response to indole-3-methanol	ISO	J:164563
Biological Process	GO:0002159	desmosome assembly	ISO	J:164563
Biological Process	GO:0002159	desmosome assembly	IMP	J:38047
Biological Process	GO:0002159	desmosome assembly	IMP	J:148138
Biological Process	GO:0002159	desmosome assembly	IMP	J:51129
Biological Process	GO:0002159	desmosome assembly	IMP	J:51129
Biological Process	GO:0050982	detection of mechanical stimulus	ISO	J:164563
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0098911	regulation of ventricular cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0043588	skin development	IMP	J:38047