Kcna1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
MGI:96654

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IDA	J:215654
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:226018
Molecular Function	GO:0005515	protein binding	IPI	J:230557
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:155856
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IDA	J:215654
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:170639
Cellular Component	GO:0030424	axon	IDA	J:226018
Cellular Component	GO:0030424	axon	IDA	J:19538
Cellular Component	GO:0043194	axon initial segment	IDA	J:149503
Cellular Component	GO:0043679	axon terminus	IDA	J:170639
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IDA	J:19538
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:201521
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:19538
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0030425	dendrite	IDA	J:201521
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0044224	juxtaparanode region of axon	ISO	J:164563
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:215893
Cellular Component	GO:0044224	juxtaparanode region of axon	ISO	J:155856
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:85502
Cellular Component	GO:0044224	juxtaparanode region of axon	IBA	J:265628
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:19538
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IDA	J:201521
Cellular Component	GO:0033270	paranode region of axon	IDA	J:19538
Cellular Component	GO:0033270	paranode region of axon	ISO	J:155856
Cellular Component	GO:0033270	paranode region of axon	ISO	J:164563
Cellular Component	GO:0033270	paranode region of axon	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	IDA	J:226018
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IMP	J:215654
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0034705	potassium channel complex	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:19538
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:215893
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0007420	brain development	IMP	J:178006
Biological Process	GO:0010644	cell communication by electrical coupling	ISO	J:155856
Biological Process	GO:0071286	cellular response to magnesium ion	IMP	J:217265
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	IMP	J:197938
Biological Process	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch	IMP	J:197938
Biological Process	GO:0021766	hippocampus development	IMP	J:217281
Biological Process	GO:0010960	magnesium ion homeostasis	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:217281
Biological Process	GO:0050905	neuromuscular process	IMP	J:77281
Biological Process	GO:0050905	neuromuscular process	ISO	J:164563
Biological Process	GO:0019228	neuronal action potential	IMP	J:77281
Biological Process	GO:0019228	neuronal action potential	ISO	J:155856
Biological Process	GO:0023041	neuronal signal transduction	ISO	J:155856
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IDA	J:215654
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	IEA	J:72247
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:0051260	protein homooligomerization	IEA	J:72247
Biological Process	GO:0008104	protein localization	ISO	J:155856
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006937	regulation of muscle contraction	ISO	J:155856
Biological Process	GO:0001964	startle response	IMP	J:178006
Biological Process	GO:0001964	startle response	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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