GO Annotations Graph

• Symbol: Kcna5
• Name: potassium voltage-gated channel, shaker-related subfamily, member 5
• ID: MGI:96662

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051393	alpha-actinin binding	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:255706
Molecular Function	GO:0005515	protein binding	IPI	J:95586
Molecular Function	GO:0005515	protein binding	IPI	J:95586
Molecular Function	GO:0005515	protein binding	IPI	J:140247
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	ISO	J:164563
Molecular Function	GO:0086087	voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization	ISO	J:164563
Molecular Function	GO:0086090	voltage-gated potassium channel activity involved in SA node cell action potential repolarization	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:164563
Cellular Component	GO:0014704	intercalated disc	IDA	J:140247
Cellular Component	GO:0046691	intracellular canaliculus	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:140247
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:95586
Cellular Component	GO:0034705	potassium channel complex	ISO	J:155856
Cellular Component	GO:0034705	potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Biological Process	GO:0086014	atrial cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0060081	membrane hyperpolarization	ISO	J:164563
Biological Process	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0086050	membrane repolarization during bundle of His cell action potential	ISO	J:164563
Biological Process	GO:0086052	membrane repolarization during SA node cell action potential	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:216917
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:155856
Biological Process	GO:2000288	positive regulation of myoblast proliferation	ISO	J:155856
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:164563
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:155856
Biological Process	GO:0055075	potassium ion homeostasis	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:31578
Biological Process	GO:0051259	protein complex oligomerization	ISO	J:155856
Biological Process	GO:0051260	protein homooligomerization	IEA	J:72247
Biological Process	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization	ISO	J:164563
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:155856
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:95586
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:95586
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0043266	regulation of potassium ion transport	ISO	J:164563
Biological Process	GO:0019229	regulation of vasoconstriction	IMP	J:70694
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247