GO Annotations Graph

• Symbol: Kcnb1
• Name: potassium voltage gated channel, Shab-related subfamily, member 1
• ID: MGI:96666

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IMP	J:220501
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IMP	J:129963
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IDA	J:200490
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200490
Molecular Function	GO:0005515	protein binding	IPI	J:31578
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:90589
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:200490
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0032809	neuronal cell body membrane	IDA	J:200490
Cellular Component	GO:0032809	neuronal cell body membrane	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:129963
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IBA	J:265628
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:1990635	proximal dendrite	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:200490
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0001508	action potential	ISO	J:155856
Biological Process	GO:0001508	action potential	ISO	J:164563
Biological Process	GO:0001508	action potential	IBA	J:265628
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:155856
Biological Process	GO:0071333	cellular response to glucose stimulus	IDA	J:129963
Biological Process	GO:0031669	cellular response to nutrient levels	ISO	J:155856
Biological Process	GO:0045163	clustering of voltage-gated potassium channels	ISO	J:155856
Biological Process	GO:0006887	exocytosis	IEA	J:60000
Biological Process	GO:0042593	glucose homeostasis	IMP	J:129963
Biological Process	GO:0007215	glutamate receptor signaling pathway	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0046676	negative regulation of insulin secretion	IMP	J:129963
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	ISO	J:155856
Biological Process	GO:0033605	positive regulation of catecholamine secretion	ISO	J:155856
Biological Process	GO:1900454	positive regulation of long-term synaptic depression	IMP	J:220501
Biological Process	GO:0010701	positive regulation of norepinephrine secretion	ISO	J:155856
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:155856
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:220501
Biological Process	GO:0071805	potassium ion transmembrane transport	IDA	J:200490
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:129963
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0006813	potassium ion transport	ISO	J:90589
Biological Process	GO:0051260	protein homooligomerization	IEA	J:72247
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0098900	regulation of action potential	IMP	J:129963
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:2000671	regulation of motor neuron apoptotic process	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0006904	vesicle docking involved in exocytosis	ISO	J:155856