GO Annotations Graph

• Symbol: Kcnc2
• Name: potassium voltage gated channel, Shaw-related subfamily, member 2
• ID: MGI:96668

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:219112
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:219188
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0030673	axolemma	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:219112
Cellular Component	GO:0030425	dendrite	IDA	J:219188
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	IBA	J:265628
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:219188
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0032809	neuronal cell body membrane	IDA	J:219112
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0032809	neuronal cell body membrane	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	IDA	J:219188
Cellular Component	GO:0043204	perikaryon	IDA	J:219112
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:219112
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:219112
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0001508	action potential	IMP	J:140824
Biological Process	GO:0071732	cellular response to nitric oxide	ISO	J:155856
Biological Process	GO:0097237	cellular response to toxic substance	ISO	J:155856
Biological Process	GO:0034220	monoatomic ion transmembrane transport	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0038060	nitric oxide-cGMP-mediated signaling pathway	ISO	J:155856
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:0006813	potassium ion transport	IEA	J:72247
Biological Process	GO:0051291	protein heterooligomerization	ISO	J:155856
Biological Process	GO:0051260	protein homooligomerization	ISO	J:155856
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247