Kcne1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kcne1
potassium voltage-gated channel, Isk-related subfamily, member 1
MGI:96673

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0015459	potassium channel regulator activity	ISO	J:155856
Molecular Function	GO:0015459	potassium channel regulator activity	IDA	J:36442
Molecular Function	GO:0015459	potassium channel regulator activity	ISO	J:164563
Molecular Function	GO:0015459	potassium channel regulator activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0031433	telethonin binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	ISO	J:164563
Molecular Function	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108905
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108905
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:121998
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	ISO	J:164563
Biological Process	GO:0071468	cellular response to acidic pH	ISO	J:155856
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:164563
Biological Process	GO:0002070	epithelial cell maturation	IMP	J:108905
Biological Process	GO:0060047	heart contraction	IMP	J:105415
Biological Process	GO:0086009	membrane repolarization	ISO	J:164563
Biological Process	GO:0086011	membrane repolarization during action potential	ISO	J:164563
Biological Process	GO:0086011	membrane repolarization during action potential	IBA	J:265628
Biological Process	GO:0086013	membrane repolarization during cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	ISO	J:164563
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	ISO	J:155856
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	IBA	J:265628
Biological Process	GO:0090315	negative regulation of protein targeting to membrane	ISO	J:155856
Biological Process	GO:1903817	negative regulation of voltage-gated potassium channel activity	ISO	J:155856
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	ISO	J:155856
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	ISO	J:155856
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:164563
Biological Process	GO:0097623	potassium ion export across plasma membrane	IBA	J:265628
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:106204
Biological Process	GO:0006813	potassium ion transport	IEA	J:72247
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:1902259	regulation of delayed rectifier potassium channel activity	ISO	J:164563
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	IBA	J:265628
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	IMP	J:105415
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	ISO	J:164563
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	IBA	J:265628
Biological Process	GO:0033363	secretory granule organization	IMP	J:106204
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	IBA	J:265628
Biological Process	GO:0021750	vestibular nucleus development	IMP	J:108905

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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