Kras GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kras
Kirsten rat sarcoma viral oncogene homolog
MGI:96680

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:155856
Molecular Function	GO:0019003	GDP binding	IBA	J:265628
Molecular Function	GO:0019002	GMP binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	TAS	J:58245
Molecular Function	GO:0003924	GTPase activity	IGI	J:95509
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0030275	LRR domain binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:190126
Molecular Function	GO:0005515	protein binding	IPI	J:163128
Molecular Function	GO:0005515	protein binding	IPI	J:245378
Molecular Function	GO:0005515	protein binding	IPI	J:245708
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IDA	J:327412
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:195239
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:327412
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:53886
Cellular Component	GO:0016020	membrane	IGI	J:88170
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9029152
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9682572
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-1250468
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-1250472
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:95509
Biological Process	GO:0008283	cell population proliferation	IGI	J:95509
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0038002	endocrine signaling	IMP	J:215828
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IGI	J:202949
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IDA	J:202949
Biological Process	GO:0021897	forebrain astrocyte development	IMP	J:188377
Biological Process	GO:0014009	glial cell proliferation	IGI	J:95509
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IGI	J:214268
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	ISO	J:327400
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IDA	J:202949
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63722
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:2000774	positive regulation of cellular senescence	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:188377
Biological Process	GO:0060252	positive regulation of glial cell proliferation	IGI	J:95509
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:155856
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:155856
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0035022	positive regulation of Rac protein signal transduction	IGI	J:95509
Biological Process	GO:0016601	Rac protein signal transduction	IGI	J:95509
Biological Process	GO:0016601	Rac protein signal transduction	IGI	J:95509
Biological Process	GO:0007265	Ras protein signal transduction	IBA	J:265628
Biological Process	GO:0007265	Ras protein signal transduction	IGI	J:95509
Biological Process	GO:0007265	Ras protein signal transduction	IMP	J:188377
Biological Process	GO:0007265	Ras protein signal transduction	TAS	J:58245
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IGI	J:74257
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	IGI	J:74257
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0035914	skeletal muscle cell differentiation	IGI	J:94087
Biological Process	GO:0051146	striated muscle cell differentiation	IGI	J:94087
Biological Process	GO:0060509	type I pneumocyte differentiation	IDA	J:202949
Biological Process	GO:0008542	visual learning	IGI	J:74257

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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