GO Annotations Graph

• Symbol: Krt18
• Name: keratin 18
• ID: MGI:96692

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:236209
Molecular Function	GO:0005515	protein binding	IPI	J:322687
Molecular Function	GO:0005515	protein binding	IPI	J:121814
Molecular Function	GO:0005515	protein binding	IPI	J:121814
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0005198	structural molecule activity	IEA	J:72247
Cellular Component	GO:0071944	cell periphery	IDA	J:195630
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005882	intermediate filament	ISO	J:164563
Cellular Component	GO:0005882	intermediate filament	IDA	J:121814
Cellular Component	GO:0045095	keratin filament	ISO	J:155856
Cellular Component	GO:0045095	keratin filament	ISO	J:164563
Cellular Component	GO:0045095	keratin filament	IBA	J:265628
Cellular Component	GO:0045095	keratin filament	IDA	J:177729
Cellular Component	GO:0005815	microtubule organizing center	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IMP	J:121814
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	ISO	J:164563
Biological Process	GO:0097284	hepatocyte apoptotic process	IMP	J:121814
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	ISO	J:164563
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	IBA	J:265628
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	IGI	J:121814