L1cam GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

L1cam
L1 cell adhesion molecule
MGI:96721

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IDA	J:125138
Molecular Function	GO:0042802	identical protein binding	IDA	J:38402
Molecular Function	GO:0005178	integrin binding	IDA	J:125138
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:136695
Molecular Function	GO:0005515	protein binding	IPI	J:137627
Molecular Function	GO:0005515	protein binding	IPI	J:137627
Molecular Function	GO:0005515	protein binding	IPI	J:84104
Molecular Function	GO:0005515	protein binding	IPI	J:38402
Molecular Function	GO:0005515	protein binding	IPI	J:120470
Molecular Function	GO:0005515	protein binding	IPI	J:26606
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0043621	protein self-association	IPI	J:137627
Molecular Function	GO:0033691	sialic acid binding	IDA	J:120470
Molecular Function	GO:0033691	sialic acid binding	IDA	J:158148
Cellular Component	GO:0030424	axon	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:88274
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0044294	dendritic growth cone	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:17350
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:26606
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:26606
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:106989
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:106989
Cellular Component	GO:0016020	membrane	IDA	J:120470
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-437240
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-443770
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-443785
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:106989
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:106989
Cellular Component	GO:0043195	terminal bouton	IDA	J:106989
Biological Process	GO:0061564	axon development	ISO	J:164563
Biological Process	GO:0007411	axon guidance	ISO	J:164563
Biological Process	GO:0007411	axon guidance	IGI	J:137627
Biological Process	GO:0007411	axon guidance	IGI	J:137627
Biological Process	GO:0007411	axon guidance	IMP	J:81739
Biological Process	GO:0007411	axon guidance	IMP	J:137627
Biological Process	GO:0007411	axon guidance	IDA	J:138244
Biological Process	GO:0007413	axonal fasciculation	ISO	J:155856
Biological Process	GO:0019722	calcium-mediated signaling	IDA	J:26606
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:26606
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	IMP	J:125138
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	J:125138
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IBA	J:265628
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IMP	J:125140
Biological Process	GO:0034109	homotypic cell-cell adhesion	IMP	J:26606
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IMP	J:125144
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IMP	J:125138
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	IMP	J:120470
Biological Process	GO:0031175	neuron projection development	IDA	J:120470
Biological Process	GO:0045773	positive regulation of axon extension	ISO	J:155856
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	IDA	J:26606
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IMP	J:125140
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0050808	synapse organization	ISO	J:164563
Biological Process	GO:0050808	synapse organization	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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