GO Annotations Graph

• Symbol: Lamp2
• Name: lysosomal-associated membrane protein 2
• ID: MGI:96748

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:243459
Molecular Function	GO:0005515	protein binding	IPI	J:304705
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:198895
Molecular Function	GO:0035591	signaling adaptor activity	ISO	J:164563
Cellular Component	GO:0044754	autolysosome	ISO	J:217701
Cellular Component	GO:0000421	autophagosome membrane	IDA	J:89184
Cellular Component	GO:0061742	chaperone-mediated autophagy translocation complex	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:90042
Cellular Component	GO:0005770	late endosome	ISO	J:94651
Cellular Component	GO:0031902	late endosome membrane	ISO	J:73065
Cellular Component	GO:0031902	late endosome membrane	IDA	J:176424
Cellular Component	GO:1990836	lysosomal matrix	ISO	J:73065
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:131449
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:73065
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:73065
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:176424
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0005764	lysosome	IDA	J:121457
Cellular Component	GO:0005764	lysosome	IDA	J:209071
Cellular Component	GO:0005764	lysosome	IDA	J:150327
Cellular Component	GO:0005764	lysosome	ISO	J:82579
Cellular Component	GO:0005764	lysosome	IDA	J:101737
Cellular Component	GO:0005764	lysosome	IDA	J:86243
Cellular Component	GO:0005764	lysosome	ISO	J:73065
Cellular Component	GO:0005764	lysosome	IDA	J:85207
Cellular Component	GO:0005764	lysosome	IDA	J:256294
Cellular Component	GO:0005764	lysosome	IDA	J:106780
Cellular Component	GO:0005764	lysosome	ISO	J:94651
Cellular Component	GO:0016020	membrane	ISO	J:73065
Cellular Component	GO:0016020	membrane	ISO	J:193725
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0030670	phagocytic vesicle membrane	IMP	J:115141
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0031088	platelet dense granule membrane	ISO	J:73065
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Biological Process	GO:0097352	autophagosome maturation	IMP	J:236240
Biological Process	GO:0097352	autophagosome maturation	IBA	J:265628
Biological Process	GO:0006914	autophagy	IMP	J:89184
Biological Process	GO:0009267	cellular response to starvation	IMP	J:236240
Biological Process	GO:0009267	cellular response to starvation	IBA	J:265628
Biological Process	GO:0061684	chaperone-mediated autophagy	IGI	J:140356
Biological Process	GO:0061684	chaperone-mediated autophagy	IMP	J:236240
Biological Process	GO:0061684	chaperone-mediated autophagy	ISO	J:164563
Biological Process	GO:0061684	chaperone-mediated autophagy	ISO	J:155856
Biological Process	GO:0061684	chaperone-mediated autophagy	ISO	J:164563
Biological Process	GO:0061684	chaperone-mediated autophagy	IMP	J:140365
Biological Process	GO:1905146	lysosomal protein catabolic process	ISO	J:164563
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:156684
Biological Process	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	ISO	J:164563
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	IMP	J:198895
Biological Process	GO:0006605	protein targeting	IMP	J:236240
Biological Process	GO:0006605	protein targeting	IMP	J:89184
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	ISO	J:164563
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	IMP	J:236240
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	IBA	J:265628
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	ISO	J:73065
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563