GO Annotations Graph

• Symbol: Lgals3
• Name: lectin, galactose binding, soluble 3
• ID: MGI:96778

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050785	advanced glycation end-product receptor activity	ISO	J:155856
Molecular Function	GO:0030246	carbohydrate binding	ISO	J:164563
Molecular Function	GO:0042056	chemoattractant activity	ISO	J:164563
Molecular Function	GO:0048030	disaccharide binding	ISO	J:155856
Molecular Function	GO:0034988	Fc-gamma receptor I complex binding	ISO	J:155856
Molecular Function	GO:0019863	IgE binding	ISO	J:155856
Molecular Function	GO:0019863	IgE binding	ISO	J:164563
Molecular Function	GO:0019863	IgE binding	IBA	J:265628
Molecular Function	GO:0043236	laminin binding	ISO	J:164563
Molecular Function	GO:0043236	laminin binding	IBA	J:265628
Molecular Function	GO:0140693	molecular condensate scaffold activity	ISO	J:164563
Molecular Function	GO:0048029	monosaccharide binding	ISO	J:155856
Molecular Function	GO:0070492	oligosaccharide binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:258853
Molecular Function	GO:0005515	protein binding	IPI	J:172885
Molecular Function	GO:0005515	protein binding	IPI	J:258853
Molecular Function	GO:0005515	protein binding	IPI	J:76353
Molecular Function	GO:0005515	protein binding	IPI	J:61468
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:219172
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0001533	cornified envelope	IDA	J:230728
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	IDA	J:61468
Cellular Component	GO:0005737	cytoplasm	IDA	J:76353
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:194920
Cellular Component	GO:0031012	extracellular matrix	IDA	J:100747
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8878599
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0097386	glial cell projection	IDA	J:164294
Cellular Component	GO:0001772	immunological synapse	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	IDA	J:151990
Cellular Component	GO:0001772	immunological synapse	IBA	J:265628
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:61468
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005681	spliceosomal complex	IEA	J:60000
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0048245	eosinophil chemotaxis	ISO	J:164563
Biological Process	GO:0048245	eosinophil chemotaxis	IBA	J:265628
Biological Process	GO:0030198	extracellular matrix organization	IGI	J:100747
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0031640	killing of cells of another organism	ISO	J:164563
Biological Process	GO:0048246	macrophage chemotaxis	ISO	J:164563
Biological Process	GO:0048246	macrophage chemotaxis	IBA	J:265628
Biological Process	GO:0002548	monocyte chemotaxis	ISO	J:164563
Biological Process	GO:0002548	monocyte chemotaxis	IBA	J:265628
Biological Process	GO:0071674	mononuclear cell migration	ISO	J:164563
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1903769	negative regulation of cell proliferation in bone marrow	ISO	J:155856
Biological Process	GO:0045806	negative regulation of endocytosis	IMP	J:151990
Biological Process	GO:0045806	negative regulation of endocytosis	ISO	J:164563
Biological Process	GO:0045806	negative regulation of endocytosis	IBA	J:265628
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:2000521	negative regulation of immunological synapse formation	IMP	J:151990
Biological Process	GO:2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	IMP	J:151990
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	IMP	J:151990
Biological Process	GO:0030593	neutrophil chemotaxis	ISO	J:164563
Biological Process	GO:0030593	neutrophil chemotaxis	IBA	J:265628
Biological Process	GO:0050918	positive chemotaxis	ISO	J:164563
Biological Process	GO:0050918	positive chemotaxis	IBA	J:265628
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0090280	positive regulation of calcium ion import	ISO	J:164563
Biological Process	GO:0090280	positive regulation of calcium ion import	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0071677	positive regulation of mononuclear cell migration	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0014064	positive regulation of serotonin secretion	ISO	J:155856
Biological Process	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	ISO	J:164563
Biological Process	GO:0070232	regulation of T cell apoptotic process	ISO	J:164563
Biological Process	GO:0042129	regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0001501	skeletal system development	IGI	J:100747