GO Annotations Graph

• Symbol: Lhcgr
• Name: luteinizing hormone/choriogonadotropin receptor
• ID: MGI:96783

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:0038106	choriogonadotropin hormone binding	IDA	J:183230
Molecular Function	GO:0035472	choriogonadotropin hormone receptor activity	IDA	J:183230
Molecular Function	GO:0035472	choriogonadotropin hormone receptor activity	IMP	J:66818
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	ISO	J:155856
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0004964	luteinizing hormone receptor activity	ISO	J:164563
Molecular Function	GO:0004964	luteinizing hormone receptor activity	IBA	J:265628
Molecular Function	GO:0004964	luteinizing hormone receptor activity	TAS	J:1862
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:155856
Molecular Function	GO:0016500	protein-hormone receptor activity	IEA	J:72247
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:183230
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:155856
Biological Process	GO:0007190	activation of adenylate cyclase activity	ISO	J:155856
Biological Process	GO:0007190	activation of adenylate cyclase activity	IDA	J:183230
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:183230
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0050482	arachidonic acid secretion	ISO	J:155856
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	IDA	J:183230
Biological Process	GO:0071373	cellular response to luteinizing hormone stimulus	ISO	J:164563
Biological Process	GO:0050890	cognition	ISO	J:164563
Biological Process	GO:0046544	development of secondary male sexual characteristics	IMP	J:66818
Biological Process	GO:0008585	female gonad development	IMP	J:99642
Biological Process	GO:0008585	female gonad development	IMP	J:66818
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0042700	luteinizing hormone signaling pathway	ISO	J:155856
Biological Process	GO:0042700	luteinizing hormone signaling pathway	ISO	J:164563
Biological Process	GO:0042700	luteinizing hormone signaling pathway	IBA	J:265628
Biological Process	GO:0008584	male gonad development	IBA	J:265628
Biological Process	GO:0008584	male gonad development	IMP	J:66818
Biological Process	GO:0001541	ovarian follicle development	IBA	J:265628
Biological Process	GO:0001541	ovarian follicle development	IMP	J:66818
Biological Process	GO:0022602	ovulation cycle process	IBA	J:265628
Biological Process	GO:0022602	ovulation cycle process	IMP	J:66818
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IDA	J:183230
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0010524	positive regulation of calcium ion transport into cytosol	ISO	J:155856
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	ISO	J:155856
Biological Process	GO:0046886	positive regulation of hormone biosynthetic process	ISO	J:155856
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	IDA	J:183230
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	ISO	J:155856
Biological Process	GO:0006622	protein targeting to lysosome	ISO	J:155856
Biological Process	GO:0090030	regulation of steroid hormone biosynthetic process	IMP	J:66818
Biological Process	GO:0034699	response to luteinizing hormone	ISO	J:155856
Biological Process	GO:0072520	seminiferous tubule development	IMP	J:66818
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0007283	spermatogenesis	IMP	J:66818
Biological Process	GO:0060065	uterus development	IMP	J:66818