GO Annotations Graph

• Symbol: Lox
• Name: lysyl oxidase
• ID: MGI:96817

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005518	collagen binding	ISO	J:164563
Molecular Function	GO:0005507	copper ion binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:275672
Molecular Function	GO:0005515	protein binding	IPI	J:172658
Molecular Function	GO:0005515	protein binding	IPI	J:143612
Molecular Function	GO:0005515	protein binding	IPI	J:154659
Molecular Function	GO:0005515	protein binding	IPI	J:105910
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	ISO	J:164563
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:237691
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	ISO	J:155856
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IBA	J:265628
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:101687
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:5777
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:101687
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:5880
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:5880
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	IDA	J:88033
Molecular Function	GO:0036094	small molecule binding	ISO	J:164563
Cellular Component	GO:0005581	collagen trimer	IDA	J:17962
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IBA	J:265628
Cellular Component	GO:0031012	extracellular matrix	IDA	J:220322
Cellular Component	GO:0031012	extracellular matrix	IDA	J:44769
Cellular Component	GO:0031012	extracellular matrix	IDA	J:143612
Cellular Component	GO:0031012	extracellular matrix	ISO	J:73065
Cellular Component	GO:0005576	extracellular region	IDA	J:237691
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Biological Process	GO:0035904	aorta development	IMP	J:222159
Biological Process	GO:0035905	ascending aorta development	IMP	J:243826
Biological Process	GO:0001568	blood vessel development	IMP	J:103389
Biological Process	GO:0001568	blood vessel development	IMP	J:103389
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:237691
Biological Process	GO:0030282	bone mineralization	IMP	J:214651
Biological Process	GO:0060326	cell chemotaxis	IMP	J:140364
Biological Process	GO:0060326	cell chemotaxis	ISO	J:140364
Biological Process	GO:1990869	cellular response to chemokine	IMP	J:140364
Biological Process	GO:0071310	cellular response to organic substance	IDA	J:246444
Biological Process	GO:0030199	collagen fibril organization	ISO	J:155856
Biological Process	GO:0030199	collagen fibril organization	IBA	J:265628
Biological Process	GO:0030199	collagen fibril organization	IMP	J:230886
Biological Process	GO:0061448	connective tissue development	IGI	J:220322
Biological Process	GO:0035906	descending aorta development	IMP	J:243826
Biological Process	GO:0071897	DNA biosynthetic process	IMP	J:214651
Biological Process	GO:0048251	elastic fiber assembly	ISO	J:155856
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:103389
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:101687
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:101687
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:217970
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:103389
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:103389
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:103389
Biological Process	GO:0007507	heart development	IMP	J:222159
Biological Process	GO:0030324	lung development	IMP	J:101687
Biological Process	GO:0030324	lung development	IMP	J:101687
Biological Process	GO:0046716	muscle cell cellular homeostasis	IGI	J:220322
Biological Process	GO:0055001	muscle cell development	IMP	J:220322
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:214651
Biological Process	GO:0018057	peptidyl-lysine oxidation	ISO	J:164563
Biological Process	GO:0018057	peptidyl-lysine oxidation	IBA	J:265628
Biological Process	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	ISO	J:140364
Biological Process	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	IMP	J:140364
Biological Process	GO:0043491	protein kinase B signaling	IMP	J:254644
Biological Process	GO:0043491	protein kinase B signaling	IDA	J:254644
Biological Process	GO:0018158	protein oxidation	ISO	J:140364
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:254644
Biological Process	GO:1903010	regulation of bone development	IMP	J:176994
Biological Process	GO:0010468	regulation of gene expression	IMP	J:253826
Biological Process	GO:0045652	regulation of megakaryocyte differentiation	IMP	J:176994
Biological Process	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway	IMP	J:176994
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:143612
Biological Process	GO:1900120	regulation of receptor binding	IMP	J:140364
Biological Process	GO:1900120	regulation of receptor binding	ISO	J:140364
Biological Process	GO:0016202	regulation of striated muscle tissue development	IMP	J:220322
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	IMP	J:220322
Biological Process	GO:0009725	response to hormone	ISO	J:155856
Biological Process	GO:0048545	response to steroid hormone	ISO	J:155856
Biological Process	GO:0042060	wound healing	ISO	J:155856