GO Annotations Graph

• Symbol: Lta4h
• Name: leukotriene A4 hydrolase
• ID: MGI:96836

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004177	aminopeptidase activity	ISO	J:164563
Molecular Function	GO:0004177	aminopeptidase activity	IBA	J:265628
Molecular Function	GO:0004301	epoxide hydrolase activity	ISO	J:164563
Molecular Function	GO:0004301	epoxide hydrolase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004463	leukotriene-A4 hydrolase activity	ISO	J:155856
Molecular Function	GO:0004463	leukotriene-A4 hydrolase activity	ISO	J:164563
Molecular Function	GO:0004463	leukotriene-A4 hydrolase activity	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0070006	metalloaminopeptidase activity	ISO	J:164563
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:72247
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0045148	tripeptide aminopeptidase activity	IEA	J:72245
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0019370	leukotriene biosynthetic process	ISO	J:164563
Biological Process	GO:0019370	leukotriene biosynthetic process	IBA	J:265628
Biological Process	GO:0006691	leukotriene metabolic process	ISO	J:155856
Biological Process	GO:0043171	peptide catabolic process	ISO	J:164563
Biological Process	GO:0043171	peptide catabolic process	IBA	J:265628
Biological Process	GO:0019538	protein metabolic process	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0006508	proteolysis	IEA	J:72247