GO Annotations Graph

• Symbol: Marcks
• Name: myristoylated alanine rich protein kinase C substrate
• ID: MGI:96907

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IPI	J:240291
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005516	calmodulin binding	IPI	J:240291
Molecular Function	GO:0042802	identical protein binding	IDA	J:240291
Molecular Function	GO:0001786	phosphatidylserine binding	ISO	J:155856
Molecular Function	GO:0005543	phospholipid binding	ISO	J:155856
Molecular Function	GO:0005080	protein kinase C binding	IPI	J:51810
Cellular Component	GO:0032432	actin filament bundle	IDA	J:240291
Cellular Component	GO:0032432	actin filament bundle	IBA	J:265628
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0032059	bleb	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	IDA	J:98298
Cellular Component	GO:0005938	cell cortex	IDA	J:98298
Cellular Component	GO:0005813	centrosome	IDA	J:98298
Cellular Component	GO:0033391	chromatoid body	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:98298
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0044307	dendritic branch	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0042585	germinal vesicle	IDA	J:98298
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:85090
Cellular Component	GO:0005874	microtubule	ISO	J:155856
Cellular Component	GO:0043226	organelle	IDA	J:270211
Cellular Component	GO:0001520	outer dense fiber	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0099571	postsynaptic cytoskeleton	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0099523	presynaptic cytosol	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0051764	actin crosslink formation	IDA	J:240291
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:240291
Biological Process	GO:0007015	actin filament organization	ISO	J:155856
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0031584	activation of phospholipase D activity	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IMP	J:270211
Biological Process	GO:0031589	cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0006886	intracellular protein transport	ISO	J:155856
Biological Process	GO:0007005	mitochondrion organization	IDA	J:270211
Biological Process	GO:0021915	neural tube development	IMP	J:270211
Biological Process	GO:0022008	neurogenesis	IMP	J:270211
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:1900020	positive regulation of protein kinase C activity	ISO	J:155856
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	ISO	J:155856
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IDA	J:270211