GO Annotations Graph

• Symbol: Mbl2
• Name: mannose-binding lectin (protein C) 2
• ID: MGI:96924

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0030246	carbohydrate binding	IEA	J:60000
Molecular Function	GO:0005534	galactose binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005537	mannose binding	ISO	J:155856
Molecular Function	GO:0005537	mannose binding	ISO	J:164563
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	ISO	J:155856
Molecular Function	GO:0002020	protease binding	ISO	J:155856
Molecular Function	GO:0043621	protein self-association	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:98124
Cellular Component	GO:0005771	multivesicular body	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:1905370	serine-type endopeptidase complex	ISO	J:164563
Biological Process	GO:0140374	antiviral innate immune response	ISO	J:164563
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006958	complement activation, classical pathway	IEA	J:60000
Biological Process	GO:0001867	complement activation, lectin pathway	ISO	J:73065
Biological Process	GO:0001867	complement activation, lectin pathway	IMP	J:98124
Biological Process	GO:0001867	complement activation, lectin pathway	IDA	J:98124
Biological Process	GO:0001867	complement activation, lectin pathway	IGI	J:98124
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IGI	J:98124
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:73065
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0051873	killing by host of symbiont cells	IGI	J:98124
Biological Process	GO:0048525	negative regulation of viral process	ISO	J:164563
Biological Process	GO:0045917	positive regulation of complement activation	ISO	J:155856
Biological Process	GO:1903028	positive regulation of opsonization	ISO	J:164563
Biological Process	GO:0050766	positive regulation of phagocytosis	IBA	J:265628
Biological Process	GO:0050766	positive regulation of phagocytosis	IGI	J:98124
Biological Process	GO:0010954	positive regulation of protein processing	ISO	J:155856
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0043129	surfactant homeostasis	IBA	J:265628