GO Annotations Graph

• Symbol: Mbp
• Name: myelin basic protein
• ID: MGI:96925

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	IPI	J:240384
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0002020	protease binding	IPI	J:80712
Molecular Function	GO:0019911	structural constituent of myelin sheath	ISO	J:155856
Molecular Function	GO:0019911	structural constituent of myelin sheath	IBA	J:265628
Cellular Component	GO:0071944	cell periphery	IBA	J:265628
Cellular Component	GO:0071944	cell periphery	IDA	J:109037
Cellular Component	GO:0042995	cell projection	IDA	J:104529
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0043218	compact myelin	ISO	J:155856
Cellular Component	GO:0043218	compact myelin	IBA	J:265628
Cellular Component	GO:0043218	compact myelin	IDA	J:107700
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0033269	internode region of axon	IBA	J:265628
Cellular Component	GO:0033269	internode region of axon	IDA	J:104529
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043209	myelin sheath	ISO	J:164563
Cellular Component	GO:0043209	myelin sheath	IDA	J:240384
Cellular Component	GO:0043209	myelin sheath	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0043209	myelin sheath	IDA	J:250131
Cellular Component	GO:0043209	myelin sheath	IDA	J:105898
Cellular Component	GO:0043209	myelin sheath	IDA	J:201967
Cellular Component	GO:0043209	myelin sheath	IDA	J:167272
Cellular Component	GO:0043209	myelin sheath	IDA	J:10575
Cellular Component	GO:0043209	myelin sheath	IDA	J:104529
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IDA	J:104529
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IDA	J:240384
Biological Process	GO:0035633	maintenance of blood-brain barrier	ISO	J:164563
Biological Process	GO:0000165	MAPK cascade	ISO	J:164563
Biological Process	GO:0061024	membrane organization	IDA	J:163046
Biological Process	GO:0042552	myelination	ISO	J:155856
Biological Process	GO:0042552	myelination	IBA	J:265628
Biological Process	GO:0042552	myelination	IDA	J:88207
Biological Process	GO:0050771	negative regulation of axonogenesis	ISO	J:155856
Biological Process	GO:0034115	negative regulation of heterotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:1904685	positive regulation of metalloendopeptidase activity	ISO	J:164563
Biological Process	GO:0032570	response to progesterone	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	IDA	J:167272
Biological Process	GO:0007605	sensory perception of sound	IMP	J:119820