GO Annotations Graph

• Symbol: Rab8a
• Name: RAB8A, member RAS oncogene family
• ID: MGI:96960

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	TAS	Reactome:R-MMU-1449633
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0031489	myosin V binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:222401
Molecular Function	GO:0005515	protein binding	IPI	J:166024
Molecular Function	GO:0005515	protein binding	IPI	J:200405
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:215464
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:296099
Molecular Function	GO:0005515	protein binding	IPI	J:200405
Molecular Function	GO:0005515	protein binding	IPI	J:83108
Molecular Function	GO:0005515	protein binding	IPI	J:83108
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:208267
Cellular Component	GO:0036064	ciliary basal body	IDA	J:222401
Cellular Component	GO:0036064	ciliary basal body	IDA	J:152919
Cellular Component	GO:0097546	ciliary base	IDA	J:226310
Cellular Component	GO:0060170	ciliary membrane	IDA	J:255486
Cellular Component	GO:0005929	cilium	IMP	J:296099
Cellular Component	GO:0005929	cilium	ISO	J:164563
Cellular Component	GO:0005929	cilium	IDA	J:222401
Cellular Component	GO:0005929	cilium	ISO	J:164563
Cellular Component	GO:0005929	cilium	ISO	J:208267
Cellular Component	GO:0005929	cilium	IDA	J:206657
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	TAS	Reactome:R-MMU-1449633
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	TAS	Reactome:R-MMU-2255341
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IDA	J:161846
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0097730	non-motile cilium	ISO	J:164563
Cellular Component	GO:0097730	non-motile cilium	IDA	J:152919
Cellular Component	GO:0097730	non-motile cilium	IDA	J:161846
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:200405
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	IDA	J:200405
Cellular Component	GO:0055037	recycling endosome	IDA	J:142909
Cellular Component	GO:0055038	recycling endosome membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	IBA	J:265628
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	IBA	J:265628
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	IDA	J:124940
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0007409	axonogenesis	ISO	J:155856
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0060271	cilium assembly	IMP	J:222401
Biological Process	GO:0060271	cilium assembly	ISO	J:164563
Biological Process	GO:0060271	cilium assembly	IBA	J:265628
Biological Process	GO:0007030	Golgi organization	ISO	J:164563
Biological Process	GO:0048210	Golgi vesicle fusion to target membrane	ISO	J:164563
Biological Process	GO:0048210	Golgi vesicle fusion to target membrane	IBA	J:265628
Biological Process	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	ISO	J:155856
Biological Process	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	IBA	J:265628
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	ISO	J:155856
Biological Process	GO:0061512	protein localization to cilium	IMP	J:222401
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0009306	protein secretion	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0010506	regulation of autophagy	ISO	J:164563
Biological Process	GO:0017157	regulation of exocytosis	IBA	J:265628
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	ISO	J:155856
Biological Process	GO:0051223	regulation of protein transport	ISO	J:155856
Biological Process	GO:0006904	vesicle docking involved in exocytosis	ISO	J:164563
Biological Process	GO:0006904	vesicle docking involved in exocytosis	IBA	J:265628
Biological Process	GO:0099003	vesicle-mediated transport in synapse	ISO	J:155856