Met GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Met
met proto-oncogene
MGI:96969

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:155856
Molecular Function	GO:0005008	hepatocyte growth factor receptor activity	ISO	J:155856
Molecular Function	GO:0005008	hepatocyte growth factor receptor activity	IBA	J:265628
Molecular Function	GO:0005008	hepatocyte growth factor receptor activity	IDA	J:92782
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0043548	phosphatidylinositol 3-kinase binding	ISO	J:155856
Molecular Function	GO:0043274	phospholipase binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:206833
Molecular Function	GO:0005515	protein binding	IPI	J:322391
Molecular Function	GO:0005515	protein binding	IPI	J:143806
Molecular Function	GO:0005515	protein binding	IPI	J:190412
Molecular Function	GO:0004672	protein kinase activity	IDA	J:28570
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0017154	semaphorin receptor activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72247
Cellular Component	GO:0009925	basal plasma membrane	IBA	J:265628
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:92782
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:29402
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0036126	sperm flagellum	ISO	J:155856
Biological Process	GO:0030534	adult behavior	IMP	J:81793
Biological Process	GO:0007420	brain development	IMP	J:81793
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	ISO	J:164563
Biological Process	GO:0055013	cardiac muscle cell development	IMP	J:204089
Biological Process	GO:0060048	cardiac muscle contraction	IMP	J:204089
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:170966
Biological Process	GO:0001886	endothelial cell morphogenesis	ISO	J:164563
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:99948
Biological Process	GO:0061436	establishment of skin barrier	ISO	J:164563
Biological Process	GO:0060079	excitatory postsynaptic potential	IMP	J:170966
Biological Process	GO:0030317	flagellated sperm motility	ISO	J:155856
Biological Process	GO:0042593	glucose homeostasis	IMP	J:99948
Biological Process	GO:1904659	glucose transmembrane transport	IMP	J:99948
Biological Process	GO:1904659	glucose transmembrane transport	IMP	J:99948
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	IDA	J:92782
Biological Process	GO:0001889	liver development	IBA	J:265628
Biological Process	GO:0001889	liver development	IMP	J:28570
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:170966
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0014812	muscle cell migration	IMP	J:28570
Biological Process	GO:0014812	muscle cell migration	IMP	J:28570
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IMP	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0007517	muscle organ development	IGI	J:93807
Biological Process	GO:0051450	myoblast proliferation	IMP	J:106496
Biological Process	GO:0014902	myotube differentiation	IMP	J:28570
Biological Process	GO:0014902	myotube differentiation	IMP	J:28570
Biological Process	GO:0014902	myotube differentiation	IMP	J:28570
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:204089
Biological Process	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity	ISO	J:164563
Biological Process	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death	ISO	J:164563
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	ISO	J:155856
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0051497	negative regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0071635	negative regulation of transforming growth factor beta production	IMP	J:204089
Biological Process	GO:0007399	nervous system development	IBA	J:265628
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0001764	neuron migration	ISO	J:155856
Biological Process	GO:0031016	pancreas development	IBA	J:265628
Biological Process	GO:0006909	phagocytosis	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0001890	placenta development	IMP	J:28570
Biological Process	GO:0050918	positive chemotaxis	ISO	J:164563
Biological Process	GO:0050918	positive chemotaxis	IMP	J:203408
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:155856
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0010828	positive regulation of glucose transmembrane transport	IMP	J:99948
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0043410	positive regulation of MAPK cascade	IPI	J:92782
Biological Process	GO:0031116	positive regulation of microtubule polymerization	ISO	J:164563
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	IMP	J:204089
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:155856
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:92782
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:204089
Biological Process	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	IMP	J:85916
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	IMP	J:204089
Biological Process	GO:0032675	regulation of interleukin-6 production	IMP	J:166840
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	ISO	J:164563
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IMP	J:203408
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:28570
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:28570
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:28570
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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