GO Annotations Graph

• Symbol: Mgmt
• Name: O-6-methylguanine-DNA methyltransferase
• ID: MGI:96977

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ISO	J:155856
Molecular Function	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	IBA	J:265628
Molecular Function	GO:0008168	methyltransferase activity	IDA	J:1645
Molecular Function	GO:0008168	methyltransferase activity	IDA	J:47642
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IMP	J:60616
Biological Process	GO:0006974	DNA damage response	IMP	J:47642
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ISO	J:155856
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	IDA	J:1645
Biological Process	GO:0006281	DNA repair	IBA	J:265628
Biological Process	GO:0006281	DNA repair	IMP	J:85814
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:155856
Biological Process	GO:2000781	positive regulation of double-strand break repair	ISO	J:164563
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:85814