GO Annotations Graph

• Symbol: Mip
• Name: major intrinsic protein of lens fiber
• ID: MGI:96990

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015267	channel activity	NAS	J:113702
Molecular Function	GO:0005515	protein binding	IPI	J:132296
Molecular Function	GO:0005212	structural constituent of eye lens	IDA	J:84775
Molecular Function	GO:0015250	water channel activity	ISO	J:164563
Molecular Function	GO:0015250	water channel activity	ISO	J:155856
Molecular Function	GO:0015250	water channel activity	IBA	J:265628
Molecular Function	GO:0015250	water channel activity	IMP	J:84775
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005921	gap junction	IEA	J:60000
Cellular Component	GO:0046691	intracellular canaliculus	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	NAS	J:113702
Cellular Component	GO:0016020	membrane	IDA	J:120884
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:126208
Cellular Component	GO:0005886	plasma membrane	IDA	J:48407
Cellular Component	GO:0005886	plasma membrane	IDA	J:132296
Biological Process	GO:0015722	canalicular bile acid transport	ISO	J:155856
Biological Process	GO:0007154	cell communication	NAS	J:113702
Biological Process	GO:1990349	gap junction-mediated intercellular transport	ISO	J:164563
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:6702
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0007601	visual perception	IMP	J:84775
Biological Process	GO:0006833	water transport	ISO	J:155856
Biological Process	GO:0006833	water transport	IBA	J:265628
Biological Process	GO:0006833	water transport	IMP	J:84775