Mmp2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Mmp2
matrix metallopeptidase 2
MGI:97009

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:164563
Molecular Function	GO:0001968	fibronectin binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Molecular Function	GO:0004222	metalloendopeptidase activity	IDA	J:102661
Molecular Function	GO:0004222	metalloendopeptidase activity	IDA	J:115494
Molecular Function	GO:0008237	metallopeptidase activity	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	ISO	J:155856
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031012	extracellular matrix	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:137608
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:120811
Cellular Component	GO:0030017	sarcomere	IDA	J:120811
Biological Process	GO:0007568	aging	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0001955	blood vessel maturation	IGI	J:107674
Biological Process	GO:0001955	blood vessel maturation	IGI	J:107674
Biological Process	GO:0060346	bone trabecula formation	IGI	J:121546
Biological Process	GO:0016477	cell migration	ISO	J:155856
Biological Process	GO:0071230	cellular response to amino acid stimulus	IDA	J:164409
Biological Process	GO:0071392	cellular response to estradiol stimulus	ISO	J:155856
Biological Process	GO:0034614	cellular response to reactive oxygen species	IMP	J:122383
Biological Process	GO:0071492	cellular response to UV-A	ISO	J:164563
Biological Process	GO:0030574	collagen catabolic process	ISO	J:155856
Biological Process	GO:0030574	collagen catabolic process	IBA	J:265628
Biological Process	GO:0030574	collagen catabolic process	IMP	J:121546
Biological Process	GO:0007566	embryo implantation	IDA	J:140260
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0060325	face morphogenesis	IGI	J:121546
Biological Process	GO:0007507	heart development	ISO	J:155856
Biological Process	GO:0001957	intramembranous ossification	IGI	J:121546
Biological Process	GO:0048246	macrophage chemotaxis	ISO	J:155856
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:155856
Biological Process	GO:0045906	negative regulation of vasoconstriction	ISO	J:155856
Biological Process	GO:0001541	ovarian follicle development	ISO	J:155856
Biological Process	GO:0014012	peripheral nervous system axon regeneration	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:155856
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	IMP	J:122383
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	ISO	J:155856
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	ISO	J:155856
Biological Process	GO:1904645	response to amyloid-beta	IDA	J:273538
Biological Process	GO:0043627	response to estrogen	ISO	J:155856
Biological Process	GO:0042542	response to hydrogen peroxide	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0001666	response to hypoxia	IDA	J:124454
Biological Process	GO:0009612	response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0006979	response to oxidative stress	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0048705	skeletal system morphogenesis	IGI	J:121546
Biological Process	GO:0048771	tissue remodeling	ISO	J:155856
Biological Process	GO:0048771	tissue remodeling	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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