GO Annotations Graph

• Symbol: Mmp3
• Name: matrix metallopeptidase 3
• ID: MGI:97010

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004222	metalloendopeptidase activity	TAS	Reactome:R-MMU-2203911
Molecular Function	GO:0004222	metalloendopeptidase activity	TAS	Reactome:R-MMU-2533958
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Molecular Function	GO:0008237	metallopeptidase activity	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0044297	cell body	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:211455
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0031012	extracellular matrix	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2203911
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2533953
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2533958
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005739	mitochondrion	IDA	J:211455
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0071230	cellular response to amino acid stimulus	IDA	J:164409
Biological Process	GO:0071492	cellular response to UV-A	ISO	J:164563
Biological Process	GO:0030574	collagen catabolic process	IBA	J:265628
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0010727	negative regulation of hydrogen peroxide metabolic process	ISO	J:164563
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IMP	J:211455
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:155856
Biological Process	GO:1903209	positive regulation of oxidative stress-induced cell death	IMP	J:211455
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	IMP	J:211455
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IMP	J:211455
Biological Process	GO:0030334	regulation of cell migration	IMP	J:87729