GO Annotations Graph

• Symbol: Mpl
• Name: myeloproliferative leukemia virus oncogene
• ID: MGI:97076

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004896	cytokine receptor activity	IEA	J:72247
Molecular Function	GO:0038164	thrombopoietin receptor activity	ISO	J:164563
Molecular Function	GO:0038164	thrombopoietin receptor activity	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:1990960	basophil homeostasis	ISO	J:155856
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:199353
Biological Process	GO:1990959	eosinophil homeostasis	ISO	J:155856
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:162629
Biological Process	GO:0016064	immunoglobulin mediated immune response	IBA	J:265628
Biological Process	GO:0035702	monocyte homeostasis	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:199353
Biological Process	GO:0001780	neutrophil homeostasis	ISO	J:155856
Biological Process	GO:0030220	platelet formation	IGI	J:140200
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:199353
Biological Process	GO:0050671	positive regulation of lymphocyte proliferation	ISO	J:155856
Biological Process	GO:1905221	positive regulation of platelet formation	ISO	J:155856
Biological Process	GO:0032642	regulation of chemokine production	IMP	J:162629
Biological Process	GO:2000035	regulation of stem cell division	IMP	J:199353
Biological Process	GO:0072091	regulation of stem cell proliferation	IMP	J:199353
Biological Process	GO:0038163	thrombopoietin-mediated signaling pathway	IDA	J:261836
Biological Process	GO:0038163	thrombopoietin-mediated signaling pathway	IBA	J:265628