GO Annotations Graph

• Symbol: Mpo
• Name: myeloperoxidase
• ID: MGI:97137

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0008201	heparin binding	ISO	J:73065
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0004601	peroxidase activity	ISO	J:155856
Molecular Function	GO:0004601	peroxidase activity	IBA	J:265628
Molecular Function	GO:0004601	peroxidase activity	IDA	J:76489
Molecular Function	GO:0004601	peroxidase activity	IDA	J:53993
Molecular Function	GO:0004601	peroxidase activity	IMP	J:53993
Molecular Function	GO:0004601	peroxidase activity	IDA	J:90690
Molecular Function	GO:0004601	peroxidase activity	ISO	J:73065
Molecular Function	GO:0004601	peroxidase activity	IDA	J:73910
Cellular Component	GO:0042582	azurophil granule	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0030141	secretory granule	ISO	J:73065
Biological Process	GO:0006952	defense response	IEA	J:72247
Biological Process	GO:0042742	defense response to bacterium	IBA	J:265628
Biological Process	GO:0050832	defense response to fungus	IMP	J:53993
Biological Process	GO:0042744	hydrogen peroxide catabolic process	IMP	J:53993
Biological Process	GO:0042744	hydrogen peroxide catabolic process	ISO	J:73065
Biological Process	GO:0042744	hydrogen peroxide catabolic process	IDA	J:53993
Biological Process	GO:0002149	hypochlorous acid biosynthetic process	IMP	J:53993
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0019430	removal of superoxide radicals	IMP	J:53993
Biological Process	GO:0002679	respiratory burst involved in defense response	IMP	J:53993
Biological Process	GO:0006979	response to oxidative stress	ISO	J:155856
Biological Process	GO:0001878	response to yeast	IMP	J:53993