Myc GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Myc
myelocytomatosis oncogene
MGI:97250

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:95047
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:86265
Molecular Function	GO:0003677	DNA binding	IDA	J:85481
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:168649
Molecular Function	GO:0005515	protein binding	IPI	J:175130
Molecular Function	GO:0005515	protein binding	IPI	J:177147
Molecular Function	GO:0005515	protein binding	IPI	J:177147
Molecular Function	GO:0005515	protein binding	IPI	J:145909
Molecular Function	GO:0005515	protein binding	IPI	J:240581
Molecular Function	GO:0005515	protein binding	IPI	J:165999
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:193629
Molecular Function	GO:0005515	protein binding	IPI	J:193629
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:138546
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:197300
Cellular Component	GO:0030424	axon	IDA	J:57340
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0000791	euchromatin	IDA	J:185349
Cellular Component	GO:0071943	Myc-Max complex	ISO	J:164563
Cellular Component	GO:0071943	Myc-Max complex	IPI	J:165999
Cellular Component	GO:0016604	nuclear body	IDA	J:97160
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9634437
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:197300
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:204122
Cellular Component	GO:0005634	nucleus	IDA	J:124280
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:75047
Cellular Component	GO:0005634	nucleus	ISO	J:99527
Cellular Component	GO:0005634	nucleus	IDA	J:138546
Cellular Component	GO:0005634	nucleus	IDA	J:124280
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:197300
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0090571	RNA polymerase II transcription repressor complex	ISO	J:164563
Cellular Component	GO:0005819	spindle	IDA	J:93217
Biological Process	GO:1990863	acinar cell proliferation	IGI	J:124123
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:86000
Biological Process	GO:0006865	amino acid transport	ISO	J:155856
Biological Process	GO:0001783	B cell apoptotic process	IMP	J:115648
Biological Process	GO:0001783	B cell apoptotic process	IGI	J:72281
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:144178
Biological Process	GO:0008283	cell population proliferation	ISO	J:155856
Biological Process	GO:0008283	cell population proliferation	IGI	J:124123
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0035457	cellular response to interferon-alpha	IDA	J:211286
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:180570
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0051276	chromosome organization	ISO	J:164563
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:121871
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IDA	J:158685
Biological Process	GO:0006351	DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006352	DNA-templated transcription initiation	ISO	J:155856
Biological Process	GO:0070371	ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0006006	glucose metabolic process	ISO	J:155856
Biological Process	GO:0007007	inner mitochondrial membrane organization	ISO	J:155856
Biological Process	GO:0006879	intracellular iron ion homeostasis	ISO	J:164563
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:86000
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IDA	J:86000
Biological Process	GO:0046722	lactic acid secretion	ISO	J:155856
Biological Process	GO:0000165	MAPK cascade	ISO	J:164563
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:121871
Biological Process	GO:0014902	myotube differentiation	IMP	J:178918
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0051782	negative regulation of cell division	ISO	J:164563
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0046325	negative regulation of glucose import	ISO	J:155856
Biological Process	GO:0045656	negative regulation of monocyte differentiation	ISO	J:164563
Biological Process	GO:0032091	negative regulation of protein binding	IDA	J:131331
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:78823
Biological Process	GO:0001866	NK T cell proliferation	IMP	J:150019
Biological Process	GO:0001866	NK T cell proliferation	IMP	J:150019
Biological Process	GO:0001866	NK T cell proliferation	IMP	J:150019
Biological Process	GO:0043473	pigmentation	IMP	J:121871
Biological Process	GO:1904699	positive regulation of acinar cell proliferation	IGI	J:124123
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IMP	J:86000
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IDA	J:86000
Biological Process	GO:2001171	positive regulation of ATP biosynthetic process	ISO	J:155856
Biological Process	GO:0002904	positive regulation of B cell apoptotic process	IGI	J:72281
Biological Process	GO:0043085	positive regulation of catalytic activity	IMP	J:124454
Biological Process	GO:0045787	positive regulation of cell cycle	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:99527
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:86000
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:79002
Biological Process	GO:1901857	positive regulation of cellular respiration	ISO	J:155856
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043388	positive regulation of DNA binding	ISO	J:155856
Biological Process	GO:1905643	positive regulation of DNA methylation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:236964
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:165999
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0060252	positive regulation of glial cell proliferation	ISO	J:155856
Biological Process	GO:0045821	positive regulation of glycolytic process	ISO	J:155856
Biological Process	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:144178
Biological Process	GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	IMP	J:144178
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	ISO	J:155856
Biological Process	GO:1903862	positive regulation of oxidative phosphorylation	ISO	J:155856
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0051973	positive regulation of telomerase activity	IMP	J:236964
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:193629
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:193629
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:193629
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:193629
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:124454
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	IDA	J:281188
Biological Process	GO:0016485	protein processing	IMP	J:115648
Biological Process	GO:0032986	protein-DNA complex disassembly	ISO	J:164563
Biological Process	GO:0006848	pyruvate transport	ISO	J:155856
Biological Process	GO:0000320	re-entry into mitotic cell cycle	ISO	J:155856
Biological Process	GO:0042981	regulation of apoptotic process	IDA	J:79002
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:193629
Biological Process	GO:0010564	regulation of cell cycle process	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:278440
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IGI	J:29949
Biological Process	GO:0006355	regulation of DNA-templated transcription	IGI	J:29949
Biological Process	GO:0006355	regulation of DNA-templated transcription	IGI	J:29949
Biological Process	GO:0010468	regulation of gene expression	IDA	J:70387
Biological Process	GO:0010468	regulation of gene expression	ISO	J:173259
Biological Process	GO:0010468	regulation of gene expression	IDA	J:70387
Biological Process	GO:0007346	regulation of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0002082	regulation of oxidative phosphorylation	ISO	J:155856
Biological Process	GO:1904672	regulation of somatic stem cell population maintenance	IDA	J:278440
Biological Process	GO:0032204	regulation of telomere maintenance	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0043279	response to alkaloid	IMP	J:115648
Biological Process	GO:0010332	response to gamma radiation	ISO	J:164563
Biological Process	GO:0009314	response to radiation	IMP	J:86000
Biological Process	GO:0009314	response to radiation	IDA	J:86000
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:121871
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:124454
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:124454
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:142037

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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