GO Annotations Graph

• Symbol: Myl2
• Name: myosin, light polypeptide 2, regulatory, cardiac, slow
• ID: MGI:97272

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003785	actin monomer binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	ISO	J:67954
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008307	structural constituent of muscle	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0097512	cardiac myofibril	ISO	J:164563
Cellular Component	GO:0043292	contractile fiber	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0030016	myofibril	ISO	J:155856
Cellular Component	GO:0030016	myofibril	IBA	J:265628
Cellular Component	GO:0030016	myofibril	IDA	J:69918
Cellular Component	GO:0016459	myosin complex	IEA	J:60000
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:155856
Biological Process	GO:0060048	cardiac muscle contraction	IBA	J:265628
Biological Process	GO:0060048	cardiac muscle contraction	IGI	J:101484
Biological Process	GO:0055003	cardiac myofibril assembly	IMP	J:45125
Biological Process	GO:0060047	heart contraction	IDA	J:114298
Biological Process	GO:0060047	heart contraction	IDA	J:69639
Biological Process	GO:0007507	heart development	IDA	J:114298
Biological Process	GO:0007507	heart development	IBA	J:265628
Biological Process	GO:0007507	heart development	IMP	J:45125
Biological Process	GO:0003007	heart morphogenesis	IGI	J:101484
Biological Process	GO:0055001	muscle cell development	IGI	J:101484
Biological Process	GO:0042694	muscle cell fate specification	IBA	J:265628
Biological Process	GO:0042694	muscle cell fate specification	IMP	J:19811
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0098735	positive regulation of the force of heart contraction	IDA	J:224740
Biological Process	GO:0009791	post-embryonic development	IGI	J:101484
Biological Process	GO:0002026	regulation of the force of heart contraction	ISO	J:155856
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	ISO	J:164563