GO Annotations Graph

• Symbol: Ncf1
• Name: neutrophil cytosolic factor 1
• ID: MGI:97283

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:239193
Molecular Function	GO:0005515	protein binding	IPI	J:45759
Molecular Function	GO:0005515	protein binding	IPI	J:45759
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:164563
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	ISO	J:164563
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	ISO	J:59323
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	ISO	J:155856
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	IBA	J:265628
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	IMP	J:64403
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	IDA	J:17309
Cellular Component	GO:0005737	cytoplasm	IDA	J:239193
Cellular Component	GO:0005737	cytoplasm	IDA	J:67554
Cellular Component	GO:0005737	cytoplasm	IDA	J:97972
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	TAS	J:63712
Cellular Component	GO:0005829	cytosol	ISO	J:59323
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0019898	extrinsic component of membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:239193
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043020	NADPH oxidase complex	ISO	J:155856
Cellular Component	GO:0043020	NADPH oxidase complex	ISO	J:164563
Cellular Component	GO:0043020	NADPH oxidase complex	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0006968	cellular defense response	IMP	J:28267
Biological Process	GO:0042742	defense response to bacterium	IMP	J:123374
Biological Process	GO:0042742	defense response to bacterium	IMP	J:39217
Biological Process	GO:0050832	defense response to fungus	IMP	J:77597
Biological Process	GO:0050832	defense response to fungus	IMP	J:100419
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:151389
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:64403
Biological Process	GO:0050665	hydrogen peroxide biosynthetic process	IMP	J:91766
Biological Process	GO:0006954	inflammatory response	IMP	J:75371
Biological Process	GO:0001909	leukocyte mediated cytotoxicity	IMP	J:123374
Biological Process	GO:0006691	leukotriene metabolic process	IMP	J:75371
Biological Process	GO:0006742	NADP catabolic process	ISO	J:59323
Biological Process	GO:0045986	negative regulation of smooth muscle contraction	IMP	J:130504
Biological Process	GO:0070947	neutrophil-mediated killing of fungus	IMP	J:151389
Biological Process	GO:0070946	neutrophil-mediated killing of gram-positive bacterium	IMP	J:151389
Biological Process	GO:1903409	reactive oxygen species biosynthetic process	ISO	J:155856
Biological Process	GO:0060264	regulation of respiratory burst involved in inflammatory response	ISO	J:155856
Biological Process	GO:0045730	respiratory burst	ISO	J:155856
Biological Process	GO:0045730	respiratory burst	IBA	J:265628
Biological Process	GO:0045730	respiratory burst	IMP	J:105077
Biological Process	GO:0045730	respiratory burst	IMP	J:105077
Biological Process	GO:0002679	respiratory burst involved in defense response	IMP	J:77597
Biological Process	GO:0009617	response to bacterium	IMP	J:60578
Biological Process	GO:0001878	response to yeast	IMP	J:77597
Biological Process	GO:0001878	response to yeast	IMP	J:151389
Biological Process	GO:0006939	smooth muscle contraction	IMP	J:130504
Biological Process	GO:0042554	superoxide anion generation	IBA	J:265628
Biological Process	GO:0042554	superoxide anion generation	IMP	J:67554
Biological Process	GO:0042554	superoxide anion generation	IMP	J:61248