GO Annotations Graph

• Symbol: Ncf2
• Name: neutrophil cytosolic factor 2
• ID: MGI:97284

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:197839
Molecular Function	GO:0005515	protein binding	IPI	J:172364
Molecular Function	GO:0005515	protein binding	IPI	J:45759
Molecular Function	GO:0005515	protein binding	IPI	J:45759
Molecular Function	GO:0005515	protein binding	IPI	J:45759
Molecular Function	GO:0031267	small GTPase binding	IPI	J:45759
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	IDA	J:45759
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	ISO	J:59323
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	ISO	J:164563
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	IBA	J:265628
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:97972
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:97972
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:59323
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043020	NADPH oxidase complex	ISO	J:164563
Biological Process	GO:0032870	cellular response to hormone stimulus	ISO	J:155856
Biological Process	GO:0006742	NADP catabolic process	ISO	J:59323
Biological Process	GO:0006909	phagocytosis	IEA	J:72247
Biological Process	GO:0045777	positive regulation of blood pressure	ISO	J:155856
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:1903426	regulation of reactive oxygen species biosynthetic process	ISO	J:155856
Biological Process	GO:0045730	respiratory burst	IEA	J:72247
Biological Process	GO:0009749	response to glucose	ISO	J:155856
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:155856
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0042554	superoxide anion generation	ISO	J:164563
Biological Process	GO:0042554	superoxide anion generation	IBA	J:265628
Biological Process	GO:0042554	superoxide anion generation	IDA	J:45759
Biological Process	GO:0006801	superoxide metabolic process	ISO	J:59323