GO Annotations Graph

• Symbol: Ncl
• Name: nucleolin
• ID: MGI:97286

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0044547	DNA topoisomerase binding	ISO	J:164563
Molecular Function	GO:1990631	ErbB-4 class receptor binding	ISO	J:155856
Molecular Function	GO:0042393	histone binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0043560	insulin receptor substrate binding	IPI	J:230404
Molecular Function	GO:0043560	insulin receptor substrate binding	IPI	J:230404
Molecular Function	GO:0043236	laminin binding	ISO	J:155856
Molecular Function	GO:0048027	mRNA 5'-UTR binding	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0042731	PH domain binding	IPI	J:230404
Molecular Function	GO:0042731	PH domain binding	IPI	J:230404
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:166693
Molecular Function	GO:0005515	protein binding	IPI	J:213624
Molecular Function	GO:0005515	protein binding	IPI	J:231210
Molecular Function	GO:0005515	protein binding	IPI	J:79740
Molecular Function	GO:0005515	protein binding	IPI	J:244072
Molecular Function	GO:0005515	protein binding	IPI	J:172192
Molecular Function	GO:0005515	protein binding	IPI	J:163041
Molecular Function	GO:0005515	protein binding	IPI	J:157813
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	IDA	J:128459
Molecular Function	GO:0042134	rRNA primary transcript binding	ISO	J:155856
Molecular Function	GO:0035368	selenocysteine insertion sequence binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0042162	telomeric DNA binding	ISO	J:164563
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0001533	cornified envelope	IDA	J:230728
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0001651	dense fibrillar component	ISO	J:155856
Cellular Component	GO:0001650	fibrillar center	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	IDA	J:128459
Cellular Component	GO:0005730	nucleolus	IDA	J:32712
Cellular Component	GO:0005730	nucleolus	IDA	J:87744
Cellular Component	GO:0005730	nucleolus	IDA	J:92518
Cellular Component	GO:0005730	nucleolus	IDA	J:204475
Cellular Component	GO:0005730	nucleolus	IDA	J:32712
Cellular Component	GO:0005730	nucleolus	ISO	J:73065
Cellular Component	GO:0005730	nucleolus	IDA	J:32712
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IDA	J:128459
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:39351
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:142821
Cellular Component	GO:0005681	spliceosomal complex	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	IDA	J:34905
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:155856
Biological Process	GO:0006897	endocytosis	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	IDA	J:230404
Biological Process	GO:0017148	negative regulation of translation	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:155856
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	IDA	J:230404
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	IDA	J:230404
Biological Process	GO:2000232	regulation of rRNA processing	ISO	J:155856