Nedd4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nedd4
neural precursor cell expressed, developmentally down-regulated 4
MGI:97297

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031698	beta-2 adrenergic receptor binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	IDA	J:230617
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0050815	phosphoserine residue binding	IDA	J:140385
Molecular Function	GO:0050816	phosphothreonine residue binding	IDA	J:140385
Molecular Function	GO:0070064	proline-rich region binding	ISO	J:164563
Molecular Function	GO:0070064	proline-rich region binding	IPI	J:75315
Molecular Function	GO:0070064	proline-rich region binding	IPI	J:140926
Molecular Function	GO:0070064	proline-rich region binding	IPI	J:140926
Molecular Function	GO:0005515	protein binding	IPI	J:244072
Molecular Function	GO:0005515	protein binding	IPI	J:56881
Molecular Function	GO:0005515	protein binding	IPI	J:164745
Molecular Function	GO:0005515	protein binding	IPI	J:159070
Molecular Function	GO:0005515	protein binding	IPI	J:122283
Molecular Function	GO:0005515	protein binding	IPI	J:65663
Molecular Function	GO:0005515	protein binding	IPI	J:122283
Molecular Function	GO:0005515	protein binding	IPI	J:187910
Molecular Function	GO:0005515	protein binding	IPI	J:164713
Molecular Function	GO:0005515	protein binding	IPI	J:178643
Molecular Function	GO:0005515	protein binding	IPI	J:164713
Molecular Function	GO:0005515	protein binding	IPI	J:164713
Molecular Function	GO:0005515	protein binding	IPI	J:65663
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0070063	RNA polymerase binding	ISO	J:164563
Molecular Function	GO:0019871	sodium channel inhibitor activity	ISO	J:164563
Molecular Function	GO:0019871	sodium channel inhibitor activity	IBA	J:265628
Molecular Function	GO:0019871	sodium channel inhibitor activity	IDA	J:54531
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:164713
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:164713
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:41090
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:89097
Cellular Component	GO:0005829	cytosol	IDA	J:41090
Cellular Component	GO:0005829	cytosol	IDA	J:164173
Cellular Component	GO:0043197	dendritic spine	IDA	J:230617
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:230617
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:230617
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:230617
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:89097
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0099524	postsynaptic cytosol	IMP	J:230617
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:230617
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:230617
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0000151	ubiquitin ligase complex	IPI	J:65663
Biological Process	GO:0002250	adaptive immune response	IMP	J:143560
Biological Process	GO:0048514	blood vessel morphogenesis	IGI	J:159895
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:159895
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0003197	endocardial cushion development	IGI	J:159895
Biological Process	GO:0003197	endocardial cushion development	IMP	J:159895
Biological Process	GO:0051649	establishment of localization in cell	IDA	J:54531
Biological Process	GO:0044111	formation of structure involved in a symbiotic process	ISO	J:164563
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0007041	lysosomal transport	ISO	J:164563
Biological Process	GO:2000650	negative regulation of sodium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:2000650	negative regulation of sodium ion transmembrane transporter activity	IBA	J:265628
Biological Process	GO:0010766	negative regulation of sodium ion transport	ISO	J:164563
Biological Process	GO:0010766	negative regulation of sodium ion transport	IDA	J:54531
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:159895
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	IDA	J:159070
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0007528	neuromuscular junction development	IBA	J:265628
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:149227
Biological Process	GO:0031175	neuron projection development	IBA	J:265628
Biological Process	GO:0003151	outflow tract morphogenesis	IGI	J:159895
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:159895
Biological Process	GO:0046824	positive regulation of nucleocytoplasmic transport	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0045732	positive regulation of protein catabolic process	IDA	J:75315
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:73065
Biological Process	GO:0050847	progesterone receptor signaling pathway	ISO	J:164563
Biological Process	GO:0070534	protein K63-linked ubiquitination	ISO	J:155856
Biological Process	GO:0006513	protein monoubiquitination	IDA	J:178643
Biological Process	GO:0006622	protein targeting to lysosome	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	IBA	J:265628
Biological Process	GO:0016567	protein ubiquitination	ISO	J:227354
Biological Process	GO:0016567	protein ubiquitination	IDA	J:41090
Biological Process	GO:0032801	receptor catabolic process	ISO	J:164563
Biological Process	GO:0032801	receptor catabolic process	IBA	J:265628
Biological Process	GO:0031623	receptor internalization	ISO	J:164563
Biological Process	GO:0031623	receptor internalization	IBA	J:265628
Biological Process	GO:0048814	regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0048814	regulation of dendrite morphogenesis	IMP	J:164745
Biological Process	GO:0048814	regulation of dendrite morphogenesis	IBA	J:265628
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	ISO	J:164563
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ISO	J:155856
Biological Process	GO:1901016	regulation of potassium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	ISO	J:155856
Biological Process	GO:0050807	regulation of synapse organization	IBA	J:265628
Biological Process	GO:0050807	regulation of synapse organization	IMP	J:149227
Biological Process	GO:0140252	regulation protein catabolic process at postsynapse	ISO	J:155856
Biological Process	GO:0006814	sodium ion transport	IDA	J:54531
Biological Process	GO:0042110	T cell activation	IMP	J:143560
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IMP	J:143560
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0046755	viral budding	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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