Nefl GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nefl
neurofilament, light polypeptide
MGI:97313

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0043274	phospholipase binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:140337
Molecular Function	GO:0005515	protein binding	IPI	J:91559
Molecular Function	GO:0005515	protein binding	IPI	J:79971
Molecular Function	GO:0005515	protein binding	IPI	J:106807
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IDA	J:206923
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ISO	J:164563
Molecular Function	GO:0005200	structural constituent of cytoskeleton	IDA	J:206923
Molecular Function	GO:0099184	structural constituent of postsynaptic intermediate filament cytoskeleton	IBA	J:265628
Molecular Function	GO:0099184	structural constituent of postsynaptic intermediate filament cytoskeleton	IDA	J:263470
Molecular Function	GO:0099184	structural constituent of postsynaptic intermediate filament cytoskeleton	IMP	J:263470
Cellular Component	GO:0030424	axon	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:33980
Cellular Component	GO:0030424	axon	IDA	J:76723
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0098981	cholinergic synapse	IMP	J:216616
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:216616
Cellular Component	GO:0005737	cytoplasm	IDA	J:206923
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0005882	intermediate filament	IDA	J:206923
Cellular Component	GO:0005882	intermediate filament	IBA	J:265628
Cellular Component	GO:0005882	intermediate filament	IDA	J:28596
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005883	neurofilament	ISO	J:155856
Cellular Component	GO:0005883	neurofilament	ISO	J:164563
Cellular Component	GO:0005883	neurofilament	IDA	J:33980
Cellular Component	GO:0005883	neurofilament	IDA	J:54791
Cellular Component	GO:0005883	neurofilament	IDA	J:92473
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:216616
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:216616
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:216616
Cellular Component	GO:0031594	neuromuscular junction	IMP	J:216616
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:74704
Cellular Component	GO:0043005	neuron projection	IDA	J:164856
Cellular Component	GO:0099160	postsynaptic intermediate filament cytoskeleton	IBA	J:265628
Cellular Component	GO:0099160	postsynaptic intermediate filament cytoskeleton	IDA	J:263470
Cellular Component	GO:0099160	postsynaptic intermediate filament cytoskeleton	IDA	J:263470
Cellular Component	GO:0099160	postsynaptic intermediate filament cytoskeleton	IDA	J:263470
Cellular Component	GO:0099160	postsynaptic intermediate filament cytoskeleton	IDA	J:263470
Cellular Component	GO:0099182	presynaptic intermediate filament cytoskeleton	IDA	J:216616
Cellular Component	GO:0099182	presynaptic intermediate filament cytoskeleton	IDA	J:216616
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263470
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:263470
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263470
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:263470
Biological Process	GO:0008089	anterograde axonal transport	ISO	J:164563
Biological Process	GO:0061564	axon development	IEA	J:72247
Biological Process	GO:0019896	axonal transport of mitochondrion	ISO	J:164563
Biological Process	GO:0007409	axonogenesis	IMP	J:42834
Biological Process	GO:0007409	axonogenesis	IMP	J:42834
Biological Process	GO:0045110	intermediate filament bundle assembly	IGI	J:206923
Biological Process	GO:0045110	intermediate filament bundle assembly	IGI	J:56931
Biological Process	GO:0045110	intermediate filament bundle assembly	IGI	J:56931
Biological Process	GO:0045109	intermediate filament organization	ISO	J:164563
Biological Process	GO:0045109	intermediate filament organization	IMP	J:77599
Biological Process	GO:0045109	intermediate filament organization	IMP	J:42834
Biological Process	GO:0045105	intermediate filament polymerization or depolymerization	ISO	J:155856
Biological Process	GO:0040011	locomotion	IMP	J:58388
Biological Process	GO:0000226	microtubule cytoskeleton organization	IMP	J:70838
Biological Process	GO:0097049	motor neuron apoptotic process	IMP	J:42834
Biological Process	GO:0097049	motor neuron apoptotic process	IMP	J:63482
Biological Process	GO:2000672	negative regulation of motor neuron apoptotic process	IMP	J:42834
Biological Process	GO:2000672	negative regulation of motor neuron apoptotic process	IMP	J:63482
Biological Process	GO:0033693	neurofilament bundle assembly	ISO	J:155856
Biological Process	GO:0033693	neurofilament bundle assembly	ISO	J:164563
Biological Process	GO:0033693	neurofilament bundle assembly	IBA	J:265628
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IGI	J:55800
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IGI	J:56931
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:113025
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:44421
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IGI	J:56931
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:86249
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:70838
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IGI	J:69136
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:58388
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:105220
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:63482
Biological Process	GO:0014012	peripheral nervous system axon regeneration	IMP	J:44421
Biological Process	GO:0050772	positive regulation of axonogenesis	IMP	J:42834
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IDA	J:263470
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IMP	J:263470
Biological Process	GO:0051258	protein polymerization	ISO	J:155856
Biological Process	GO:0031133	regulation of axon diameter	IMP	J:44421
Biological Process	GO:0031133	regulation of axon diameter	IMP	J:69136
Biological Process	GO:0090128	regulation of synapse maturation	IDA	J:216616
Biological Process	GO:0090128	regulation of synapse maturation	IMP	J:216616
Biological Process	GO:0090128	regulation of synapse maturation	IDA	J:216616
Biological Process	GO:0090128	regulation of synapse maturation	IMP	J:216616
Biological Process	GO:1903935	response to sodium arsenite	ISO	J:155856
Biological Process	GO:0008090	retrograde axonal transport	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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