GO Annotations Graph

• Symbol: Npy
• Name: neuropeptide Y
• ID: MGI:97374

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	IGI	J:47972
Molecular Function	GO:0001664	G protein-coupled receptor binding	IDA	J:60632
Molecular Function	GO:0005179	hormone activity	IEA	J:72247
Molecular Function	GO:0005184	neuropeptide hormone activity	IBA	J:265628
Molecular Function	GO:0031841	neuropeptide Y receptor binding	ISO	J:155856
Molecular Function	GO:0031841	neuropeptide Y receptor binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:211575
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	EXP	J:326643
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:326643
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:326643
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0098992	neuronal dense core vesicle	ISO	J:155856
Cellular Component	GO:0098992	neuronal dense core vesicle	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0008343	adult feeding behavior	ISO	J:155856
Biological Process	GO:0019731	antibacterial humoral response	ISO	J:164563
Biological Process	GO:0019732	antifungal humoral response	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0007631	feeding behavior	IBA	J:265628
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0042117	monocyte activation	ISO	J:155856
Biological Process	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	ISO	J:155856
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	IBA	J:265628
Biological Process	GO:0032100	positive regulation of appetite	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0045964	positive regulation of dopamine metabolic process	ISO	J:155856
Biological Process	GO:1904000	positive regulation of eating behavior	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:1904407	positive regulation of nitric oxide metabolic process	ISO	J:155856
Biological Process	GO:0008217	regulation of blood pressure	IDA	J:47972
Biological Process	GO:0032903	regulation of nerve growth factor production	ISO	J:155856
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	ISO	J:155856
Biological Process	GO:0001878	response to yeast	ISO	J:164563
Biological Process	GO:0099538	synaptic signaling via neuropeptide	IDA	J:326643
Biological Process	GO:0099538	synaptic signaling via neuropeptide	IDA	J:326643
Biological Process	GO:0099538	synaptic signaling via neuropeptide	EXP	J:326643