GO Annotations Graph

• Symbol: Ntf3
• Name: neurotrophin 3
• ID: MGI:97380

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042056	chemoattractant activity	ISO	J:164563
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Molecular Function	GO:0048406	nerve growth factor binding	ISO	J:155856
Molecular Function	GO:0005163	nerve growth factor receptor binding	IBA	J:265628
Molecular Function	GO:0005166	neurotrophin p75 receptor binding	TAS	J:58028
Molecular Function	GO:0005165	neurotrophin receptor binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:72304
Molecular Function	GO:0005515	protein binding	IPI	J:72304
Molecular Function	GO:0005515	protein binding	IPI	J:72304
Molecular Function	GO:0005102	signaling receptor binding	IEA	J:72247
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:87385
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-181788
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-181822
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-204967
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-205099
Cellular Component	GO:0008021	synaptic vesicle	IBA	J:265628
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:164563
Biological Process	GO:0032148	activation of protein kinase B activity	ISO	J:164563
Biological Process	GO:0007411	axon guidance	IDA	J:97779
Biological Process	GO:0007411	axon guidance	IMP	J:97779
Biological Process	GO:0007411	axon guidance	IMP	J:97779
Biological Process	GO:0007411	axon guidance	IMP	J:32557
Biological Process	GO:0007420	brain development	IMP	J:52951
Biological Process	GO:0048484	enteric nervous system development	IMP	J:93814
Biological Process	GO:0008544	epidermis development	IMP	J:49792
Biological Process	GO:0048699	generation of neurons	IGI	J:101705
Biological Process	GO:0007403	glial cell fate determination	IMP	J:54402
Biological Process	GO:0050930	induction of positive chemotaxis	ISO	J:164563
Biological Process	GO:0042490	mechanoreceptor differentiation	IGI	J:93853
Biological Process	GO:0042490	mechanoreceptor differentiation	IGI	J:93853
Biological Process	GO:0007613	memory	IBA	J:265628
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0042552	myelination	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IBA	J:265628
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:155580
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0021675	nerve development	IBA	J:265628
Biological Process	GO:0021675	nerve development	IMP	J:26749
Biological Process	GO:0038180	nerve growth factor signaling pathway	IBA	J:265628
Biological Process	GO:0007399	nervous system development	ISO	J:155856
Biological Process	GO:0007274	neuromuscular synaptic transmission	IDA	J:76256
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:155580
Biological Process	GO:0048666	neuron development	IMP	J:38578
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:33221
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:83461
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045687	positive regulation of glial cell differentiation	ISO	J:155856
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:83461
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:201759
Biological Process	GO:0043523	regulation of neuron apoptotic process	IDA	J:107643
Biological Process	GO:0045664	regulation of neuron differentiation	IBA	J:265628
Biological Process	GO:0051145	smooth muscle cell differentiation	IMP	J:93814
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	ISO	J:164563
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628