Ntrk1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
MGI:97383

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:155856
Molecular Function	GO:0048406	nerve growth factor binding	ISO	J:155856
Molecular Function	GO:0048406	nerve growth factor binding	ISO	J:164563
Molecular Function	GO:0010465	nerve growth factor receptor activity	ISO	J:164563
Molecular Function	GO:0043121	neurotrophin binding	IBA	J:265628
Molecular Function	GO:0005166	neurotrophin p75 receptor binding	ISO	J:155856
Molecular Function	GO:0005030	neurotrophin receptor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:231844
Molecular Function	GO:0005515	protein binding	IPI	J:154926
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0005515	protein binding	IPI	J:120306
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:207835
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:145554
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	ISO	J:237361
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:207835
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:145554
Cellular Component	GO:0009986	cell surface	IDA	J:210609
Cellular Component	GO:0005737	cytoplasm	IDA	J:71586
Cellular Component	GO:0005737	cytoplasm	IDA	J:54178
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005769	early endosome	IDA	J:210609
Cellular Component	GO:0005769	early endosome	IDA	J:207835
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0005770	late endosome	IDA	J:210609
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-198263
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-198275
Cellular Component	GO:0005886	plasma membrane	ISO	J:237361
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Biological Process	GO:0007411	axon guidance	ISO	J:155856
Biological Process	GO:0060385	axonogenesis involved in innervation	IMP	J:35563
Biological Process	GO:0030183	B cell differentiation	IMP	J:93578
Biological Process	GO:0061368	behavioral response to formalin induced pain	IMP	J:210609
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071363	cellular response to growth factor stimulus	ISO	J:145554
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:155856
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:164563
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	IBA	J:265628
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	IDA	J:210609
Biological Process	GO:0071316	cellular response to nicotine	ISO	J:155856
Biological Process	GO:0007623	circadian rhythm	IEP	J:199564
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	ISO	J:155856
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	ISO	J:155856
Biological Process	GO:0060384	innervation	IMP	J:210609
Biological Process	GO:0007611	learning or memory	ISO	J:155856
Biological Process	GO:0042490	mechanoreceptor differentiation	IMP	J:93853
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:35563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:72722
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:0038180	nerve growth factor signaling pathway	ISO	J:164563
Biological Process	GO:0038180	nerve growth factor signaling pathway	ISO	J:155856
Biological Process	GO:0038180	nerve growth factor signaling pathway	IBA	J:265628
Biological Process	GO:0038180	nerve growth factor signaling pathway	IGI	J:207835
Biological Process	GO:0038180	nerve growth factor signaling pathway	IDA	J:21389
Biological Process	GO:0038180	nerve growth factor signaling pathway	IGI	J:207835
Biological Process	GO:0007399	nervous system development	IDA	J:83805
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:72722
Biological Process	GO:0048666	neuron development	ISO	J:237361
Biological Process	GO:0031175	neuron projection development	ISO	J:237361
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	ISO	J:164563
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	ISO	J:164563
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	ISO	J:237361
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:0043068	positive regulation of programmed cell death	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	ISO	J:164563
Biological Process	GO:0051965	positive regulation of synapse assembly	IDA	J:211830
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0010623	programmed cell death involved in cell development	ISO	J:155856
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:145554
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:76516
Biological Process	GO:0051896	regulation of protein kinase B signaling	IBA	J:265628
Biological Process	GO:0014823	response to activity	ISO	J:155856
Biological Process	GO:0051602	response to electrical stimulus	ISO	J:155856
Biological Process	GO:0035094	response to nicotine	ISO	J:155856
Biological Process	GO:0031667	response to nutrient levels	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0060009	Sertoli cell development	ISO	J:155856
Biological Process	GO:0048485	sympathetic nervous system development	IMP	J:35563
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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