Ntrk3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
MGI:97385

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	ISO	J:155856
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0043121	neurotrophin binding	IBA	J:265628
Molecular Function	GO:0005030	neurotrophin receptor activity	ISO	J:164563
Molecular Function	GO:0005030	neurotrophin receptor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:322391
Molecular Function	GO:0005515	protein binding	IPI	J:225030
Molecular Function	GO:0005515	protein binding	IPI	J:201759
Molecular Function	GO:0005515	protein binding	IPI	J:72304
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:54178
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9603568
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9603580
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9603585
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	TAS	Reactome:R-MMU-9603585
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9603568
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:164563
Biological Process	GO:0032148	activation of protein kinase B activity	ISO	J:164563
Biological Process	GO:0048677	axon extension involved in regeneration	IGI	J:101705
Biological Process	GO:0048677	axon extension involved in regeneration	IGI	J:101705
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	IBA	J:265628
Biological Process	GO:0007623	circadian rhythm	IEP	J:199564
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0070306	lens fiber cell differentiation	IGI	J:189960
Biological Process	GO:0042490	mechanoreceptor differentiation	IMP	J:93853
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0022011	myelination in peripheral nervous system	IGI	J:162328
Biological Process	GO:0022011	myelination in peripheral nervous system	IGI	J:162328
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	ISO	J:155856
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0048665	neuron fate specification	ISO	J:155856
Biological Process	GO:0001764	neuron migration	ISO	J:155856
Biological Process	GO:0019227	neuronal action potential propagation	IGI	J:162328
Biological Process	GO:0019227	neuronal action potential propagation	IGI	J:162328
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IDA	J:201759
Biological Process	GO:0048691	positive regulation of axon extension involved in regeneration	IGI	J:101705
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:0050927	positive regulation of positive chemotaxis	ISO	J:164563
Biological Process	GO:0051965	positive regulation of synapse assembly	IDA	J:211830
Biological Process	GO:0097107	postsynaptic density assembly	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:155856
Biological Process	GO:0051896	regulation of protein kinase B signaling	IBA	J:265628
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	ISO	J:164563
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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