GO Annotations Graph

• Symbol: Oprd1
• Name: opioid receptor, delta 1
• ID: MGI:97438

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0038046	G protein-coupled enkephalin receptor activity	ISO	J:155856
Molecular Function	GO:0038046	G protein-coupled enkephalin receptor activity	ISO	J:164563
Molecular Function	GO:0038046	G protein-coupled enkephalin receptor activity	IBA	J:265628
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	ISO	J:164563
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	IMP	J:78285
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	IDA	J:33119
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	IDA	J:13204
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0042923	neuropeptide binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:248248
Molecular Function	GO:0033612	receptor serine/threonine kinase binding	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:33119
Cellular Component	GO:0016020	membrane	IDA	J:13204
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0098992	neuronal dense core vesicle	ISO	J:155856
Cellular Component	GO:0098992	neuronal dense core vesicle	IDA	J:326640
Cellular Component	GO:0098992	neuronal dense core vesicle	IDA	J:326640
Cellular Component	GO:0098992	neuronal dense core vesicle	IDA	J:326640
Cellular Component	GO:0098992	neuronal dense core vesicle	IDA	J:326640
Cellular Component	GO:0098992	neuronal dense core vesicle	IDA	J:326640
Cellular Component	GO:0098992	neuronal dense core vesicle	EXP	J:326640
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0097444	spine apparatus	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	J:33119
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:62551
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0097237	cellular response to toxic substance	ISO	J:164563
Biological Process	GO:0042755	eating behavior	ISO	J:155856
Biological Process	GO:0038003	G protein-coupled opioid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0038003	G protein-coupled opioid receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0007218	neuropeptide signaling pathway	IBA	J:265628
Biological Process	GO:0007218	neuropeptide signaling pathway	IDA	J:13204
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0051924	regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	ISO	J:164563
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000