GO Annotations Graph

• Symbol: Oprk1
• Name: opioid receptor, kappa 1
• ID: MGI:97439

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0038048	dynorphin receptor activity	ISO	J:164563
Molecular Function	GO:0038048	dynorphin receptor activity	IBA	J:265628
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	IDA	J:46089
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	ISO	J:164563
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	TAS	MGI:MGI:66591
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	IMP	J:237662
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0042923	neuropeptide binding	IBA	J:265628
Molecular Function	GO:0033612	receptor serine/threonine kinase binding	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:46089
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9021966
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Biological Process	GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007610	behavior	IEA	J:60000
Biological Process	GO:0048148	behavioral response to cocaine	ISO	J:155856
Biological Process	GO:0071333	cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:1990708	conditioned place preference	ISO	J:155856
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0042755	eating behavior	ISO	J:155856
Biological Process	GO:0038003	G protein-coupled opioid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0038003	G protein-coupled opioid receptor signaling pathway	TAS	MGI:MGI:66591
Biological Process	GO:0038003	G protein-coupled opioid receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0006955	immune response	ISO	J:164563
Biological Process	GO:0007626	locomotory behavior	IMP	J:46089
Biological Process	GO:0042711	maternal behavior	ISO	J:155856
Biological Process	GO:0033685	negative regulation of luteinizing hormone secretion	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	IBA	J:265628
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0033603	positive regulation of dopamine secretion	ISO	J:155856
Biological Process	GO:1904000	positive regulation of eating behavior	ISO	J:155856
Biological Process	GO:0040017	positive regulation of locomotion	ISO	J:155856
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	ISO	J:155856
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0046877	regulation of saliva secretion	IMP	J:46089
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0032868	response to insulin	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	IMP	J:46089
Biological Process	GO:0019233	sensory perception of pain	IBA	J:265628
Biological Process	GO:0050951	sensory perception of temperature stimulus	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000