GO Annotations Graph

• Symbol: Oprl1
• Name: opioid receptor-like 1
• ID: MGI:97440

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	ISO	J:164563
Molecular Function	GO:0042923	neuropeptide binding	IBA	J:265628
Molecular Function	GO:0001626	nociceptin receptor activity	IMP	J:102658
Molecular Function	GO:0001626	nociceptin receptor activity	ISO	J:164563
Molecular Function	GO:0001626	nociceptin receptor activity	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007610	behavior	IEA	J:60000
Biological Process	GO:1990708	conditioned place preference	ISO	J:155856
Biological Process	GO:0042755	eating behavior	ISO	J:155856
Biological Process	GO:0038003	G protein-coupled opioid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:0043951	negative regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	IBA	J:265628
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	ISO	J:164563
Biological Process	GO:0060454	positive regulation of gastric acid secretion	ISO	J:155856
Biological Process	GO:1904058	positive regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0035810	positive regulation of urine volume	ISO	J:155856
Biological Process	GO:1904059	regulation of locomotor rhythm	ISO	J:155856
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	IMP	J:102658
Biological Process	GO:0019233	sensory perception of pain	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:60000