Pax2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pax2
paired box 2
MGI:97486

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	IPI	J:23778
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:129070
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:83532
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:54357
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:72723
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:69176
Molecular Function	GO:0005515	protein binding	IPI	J:69176
Molecular Function	GO:0005515	protein binding	IPI	J:78851
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:72723
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:117753
Molecular Function	GO:0008134	transcription factor binding	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0005815	microtubule organizing center	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:139561
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:172881
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:57955
Cellular Component	GO:0005634	nucleus	IDA	J:57955
Cellular Component	GO:0032991	protein-containing complex	IDA	J:129070
Cellular Component	GO:0032993	protein-DNA complex	IDA	J:129070
Cellular Component	GO:0005667	transcription regulator complex	TAS	J:54357
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0048854	brain morphogenesis	IMP	J:36834
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:129294
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IGI	J:129294
Biological Process	GO:0043010	camera-type eye development	IMP	J:83532
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0001709	cell fate determination	IMP	J:83532
Biological Process	GO:0071333	cellular response to glucose stimulus	IEP	J:172981
Biological Process	GO:0071333	cellular response to glucose stimulus	IMP	J:173747
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IEP	J:172981
Biological Process	GO:0071260	cellular response to mechanical stimulus	IEP	J:120768
Biological Process	GO:0071300	cellular response to retinoic acid	IEP	J:172946
Biological Process	GO:0007417	central nervous system development	IEP	J:72
Biological Process	GO:0090102	cochlea development	IMP	J:36834
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:163537
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:36834
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:119574
Biological Process	GO:0071542	dopaminergic neuron differentiation	TAS	J:227390
Biological Process	GO:0010001	glial cell differentiation	IMP	J:36834
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:36834
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:163537
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:92326
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:119574
Biological Process	GO:0001822	kidney development	IMP	J:129294
Biological Process	GO:0001822	kidney development	IGI	J:129294
Biological Process	GO:0001822	kidney development	IMP	J:129294
Biological Process	GO:0001822	kidney development	IGI	J:129294
Biological Process	GO:0060231	mesenchymal to epithelial transition	IMP	J:30343
Biological Process	GO:0060231	mesenchymal to epithelial transition	IMP	J:30343
Biological Process	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	IEP	J:54493
Biological Process	GO:0007501	mesodermal cell fate specification	IDA	J:129070
Biological Process	GO:0072177	mesonephric duct development	IMP	J:133086
Biological Process	GO:0072177	mesonephric duct development	IEP	J:72
Biological Process	GO:0072164	mesonephric tubule development	IMP	J:133086
Biological Process	GO:0072164	mesonephric tubule development	IEP	J:72
Biological Process	GO:0072172	mesonephric tubule formation	IMP	J:172983
Biological Process	GO:0001823	mesonephros development	IMP	J:80208
Biological Process	GO:0001823	mesonephros development	IMP	J:30343
Biological Process	GO:0072205	metanephric collecting duct development	IMP	J:64394
Biological Process	GO:0072221	metanephric distal convoluted tubule development	IMP	J:120229
Biological Process	GO:0072207	metanephric epithelium development	IEP	J:172924
Biological Process	GO:0072162	metanephric mesenchymal cell differentiation	IMP	J:112694
Biological Process	GO:0072075	metanephric mesenchyme development	IDA	J:172946
Biological Process	GO:0072289	metanephric nephron tubule formation	IMP	J:120229
Biological Process	GO:0001656	metanephros development	IMP	J:30343
Biological Process	GO:0001656	metanephros development	IGI	J:80208
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:120768
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:64394
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1900215	negative regulation of apoptotic process involved in metanephric collecting duct development	IMP	J:120229
Biological Process	GO:1900218	negative regulation of apoptotic process involved in metanephric nephron tubule development	IMP	J:120229
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0072305	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	IMP	J:120229
Biological Process	GO:1900212	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	IMP	J:120229
Biological Process	GO:0043069	negative regulation of programmed cell death	IMP	J:129294
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:98488
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:98488
Biological Process	GO:0072179	nephric duct formation	IDA	J:80208
Biological Process	GO:0001843	neural tube closure	IMP	J:36834
Biological Process	GO:0061360	optic chiasma development	IMP	J:36834
Biological Process	GO:0002072	optic cup morphogenesis involved in camera-type eye development	IMP	J:36834
Biological Process	GO:0021554	optic nerve development	IMP	J:36834
Biological Process	GO:0021631	optic nerve morphogenesis	IMP	J:36834
Biological Process	GO:0021633	optic nerve structural organization	IMP	J:36834
Biological Process	GO:0031016	pancreas development	IEP	J:72
Biological Process	GO:0061205	paramesonephric duct development	IMP	J:133086
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:120229
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:145105
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:172981
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:31258
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:173744
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:117753
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:129070
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:112694
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:80208
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:120229
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:117030
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:172991
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGI	J:104408
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	IGI	J:80208
Biological Process	GO:2000594	positive regulation of metanephric DCT cell differentiation	IMP	J:120229
Biological Process	GO:0072300	positive regulation of metanephric glomerulus development	IMP	J:117753
Biological Process	GO:2000597	positive regulation of optic nerve formation	IMP	J:172973
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:72723
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:78851
Biological Process	GO:0039003	pronephric field specification	IEP	J:80208
Biological Process	GO:0048793	pronephros development	IMP	J:80208
Biological Process	GO:0043491	protein kinase B signaling	IMP	J:172981
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:172981
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:80208
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	IMP	J:120229
Biological Process	GO:0035566	regulation of metanephros size	IMP	J:145105
Biological Process	GO:0035566	regulation of metanephros size	ISO	J:164563
Biological Process	GO:0043067	regulation of programmed cell death	IGI	J:129294
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0003406	retinal pigment epithelium development	IMP	J:36834
Biological Process	GO:0048863	stem cell differentiation	IDA	J:172946
Biological Process	GO:0072189	ureter development	IMP	J:145105
Biological Process	GO:0035799	ureter maturation	IMP	J:145105
Biological Process	GO:0072197	ureter morphogenesis	IEP	J:72
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0001657	ureteric bud development	IGI	J:100569
Biological Process	GO:0001657	ureteric bud development	IGI	J:100569
Biological Process	GO:0001655	urogenital system development	IGI	J:80208
Biological Process	GO:0001655	urogenital system development	IMP	J:30343
Biological Process	GO:0001655	urogenital system development	IMP	J:30343
Biological Process	GO:0021650	vestibulocochlear nerve formation	IMP	J:36834

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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