Pck1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
MGI:97501

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016831	carboxy-lyase activity	IEA	J:60000
Molecular Function	GO:0031406	carboxylic acid binding	ISO	J:155856
Molecular Function	GO:0031406	carboxylic acid binding	ISO	J:164563
Molecular Function	GO:0019003	GDP binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0030145	manganese ion binding	ISO	J:155856
Molecular Function	GO:0030145	manganese ion binding	ISO	J:164563
Molecular Function	GO:0030145	manganese ion binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	ISO	J:155856
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	ISO	J:164563
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	IMP	J:257496
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	IBA	J:265628
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	IMP	J:63929
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	IMP	J:95004
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	IMP	J:95004
Molecular Function	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	IMP	J:63929
Molecular Function	GO:0004611	phosphoenolpyruvate carboxykinase activity	ISO	J:155856
Molecular Function	GO:0004611	phosphoenolpyruvate carboxykinase activity	IMP	J:73977
Molecular Function	GO:0106264	protein serine kinase activity (using GTP as donor)	ISO	J:164563
Molecular Function	GO:0017076	purine nucleotide binding	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9623283
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:150742
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	IBA	J:265628
Biological Process	GO:0071333	cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0071333	cellular response to glucose stimulus	ISO	J:164563
Biological Process	GO:0071333	cellular response to glucose stimulus	IBA	J:265628
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:164563
Biological Process	GO:0032869	cellular response to insulin stimulus	IBA	J:265628
Biological Process	GO:0051365	cellular response to potassium ion starvation	IDA	J:150742
Biological Process	GO:0006094	gluconeogenesis	IMP	J:257496
Biological Process	GO:0006094	gluconeogenesis	ISO	J:164563
Biological Process	GO:0006094	gluconeogenesis	ISO	J:155856
Biological Process	GO:0006094	gluconeogenesis	IBA	J:265628
Biological Process	GO:0006094	gluconeogenesis	IMP	J:63929
Biological Process	GO:0006094	gluconeogenesis	IDA	J:152724
Biological Process	GO:0006094	gluconeogenesis	IMP	J:95004
Biological Process	GO:0006094	gluconeogenesis	IMP	J:320717
Biological Process	GO:0006094	gluconeogenesis	IMP	J:95004
Biological Process	GO:0006094	gluconeogenesis	IDA	J:152724
Biological Process	GO:0006094	gluconeogenesis	IMP	J:320717
Biological Process	GO:0006094	gluconeogenesis	IMP	J:63929
Biological Process	GO:0006094	gluconeogenesis	IDA	J:76767
Biological Process	GO:0042593	glucose homeostasis	ISO	J:155856
Biological Process	GO:0006006	glucose metabolic process	ISO	J:164563
Biological Process	GO:0006006	glucose metabolic process	ISO	J:155856
Biological Process	GO:0046327	glycerol biosynthetic process from pyruvate	ISO	J:155856
Biological Process	GO:0046327	glycerol biosynthetic process from pyruvate	IBA	J:265628
Biological Process	GO:0046327	glycerol biosynthetic process from pyruvate	IMP	J:73977
Biological Process	GO:0070365	hepatocyte differentiation	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IMP	J:73977
Biological Process	GO:0006107	oxaloacetate metabolic process	ISO	J:155856
Biological Process	GO:0006107	oxaloacetate metabolic process	ISO	J:164563
Biological Process	GO:0006107	oxaloacetate metabolic process	IMP	J:257496
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	ISO	J:164563
Biological Process	GO:0043382	positive regulation of memory T cell differentiation	IMP	J:257496
Biological Process	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH	IDA	J:150742
Biological Process	GO:0019543	propionate catabolic process	IBA	J:265628
Biological Process	GO:0046890	regulation of lipid biosynthetic process	ISO	J:164563
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0032868	response to insulin	ISO	J:164563
Biological Process	GO:0042594	response to starvation	IBA	J:265628
Biological Process	GO:0072350	tricarboxylic acid metabolic process	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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