Pcna GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pcna
proliferating cell nuclear antigen
MGI:97503

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0032139	dinucleotide insertion or deletion binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0070182	DNA polymerase binding	ISO	J:164563
Molecular Function	GO:0030337	DNA polymerase processivity factor activity	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	IPI	J:202812
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0035035	histone acetyltransferase binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0032405	MutLalpha complex binding	ISO	J:164563
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:121214
Molecular Function	GO:0005515	protein binding	IPI	J:117431
Molecular Function	GO:0005515	protein binding	IPI	J:248211
Molecular Function	GO:0005515	protein binding	IPI	J:81304
Molecular Function	GO:0005515	protein binding	IPI	J:78410
Molecular Function	GO:0005515	protein binding	IPI	J:85809
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity	ISO	J:164563
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	IPI	J:142927
Cellular Component	GO:0005813	centrosome	ISO	J:204810
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IPI	J:85809
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IPI	J:85809
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:106653
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:82276
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:82276
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005652	nuclear lamina	IDA	J:81304
Cellular Component	GO:0043596	nuclear replication fork	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:202812
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:162095
Cellular Component	GO:0005634	nucleus	IDA	J:85809
Cellular Component	GO:0005634	nucleus	IDA	J:105978
Cellular Component	GO:0005634	nucleus	IDA	J:142136
Cellular Component	GO:0005634	nucleus	IDA	J:76874
Cellular Component	GO:0005634	nucleus	IDA	J:53290
Cellular Component	GO:0005634	nucleus	IDA	J:88220
Cellular Component	GO:0005634	nucleus	IDA	J:142927
Cellular Component	GO:0005634	nucleus	IDA	J:204433
Cellular Component	GO:0005634	nucleus	IDA	J:195630
Cellular Component	GO:0005634	nucleus	IDA	J:142927
Cellular Component	GO:0005634	nucleus	IDA	J:79935
Cellular Component	GO:0005634	nucleus	IDA	J:78856
Cellular Component	GO:0005634	nucleus	ISS	J:93906
Cellular Component	GO:0043626	PCNA complex	ISO	J:164563
Cellular Component	GO:0043626	PCNA complex	IBA	J:265628
Cellular Component	GO:0070557	PCNA-p21 complex	ISO	J:164563
Cellular Component	GO:0005657	replication fork	ISO	J:113839
Cellular Component	GO:0005657	replication fork	IDA	J:76360
Biological Process	GO:0006287	base-excision repair, gap-filling	IDA	J:91067
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:210952
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006260	DNA replication	IEA	J:60000
Biological Process	GO:0006272	leading strand elongation	IBA	J:265628
Biological Process	GO:0006298	mismatch repair	ISO	J:164563
Biological Process	GO:0006298	mismatch repair	IBA	J:265628
Biological Process	GO:1902990	mitotic telomere maintenance via semi-conservative replication	IGI	J:202812
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:142927
Biological Process	GO:0032077	positive regulation of deoxyribonuclease activity	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:164563
Biological Process	GO:1900264	positive regulation of DNA-directed DNA polymerase activity	ISO	J:164563
Biological Process	GO:0006275	regulation of DNA replication	IEA	J:72247
Biological Process	GO:0031297	replication fork processing	IGI	J:202812
Biological Process	GO:0033993	response to lipid	ISO	J:155856
Biological Process	GO:0019985	translesion synthesis	ISO	J:164563
Biological Process	GO:0019985	translesion synthesis	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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